• Principal Investigator for histological evaluation of chemical-induced changes in the in vitro corneal model• Mentored and led a team of eleven biologists• Worked closely with Study Directors and clients to develop experimental design• Managed and scheduled all incoming studies and paperwork • Organized and led multiple grant submissionso Coordinated grant writing between the company, private corporations, and government agencieso Researched the submission process and managed the agency accounts• Worked with Study Directors and clients to develop and transfer new in vitro assays

• Led multiple validation studies for new in vitro alternative toxicological assay systems• Oversaw the in vitro corneal histopathology processo Provided expertise in histology preparation and staining activitieso Coordinated receipt / processing / log-in of wet specimens, histology slides, and paraffin blocks• Worked with Study Directors and clients to collect information to generate study protocols• Managed laboratory budget and purchasing, including scheduling lab maintenance and equipment repairs

• Performed in vitro alternative toxicological assays (e.g. 3D tissue culture assays, 96-well based assays)• Conducted cryostat sectioning and staining for various tissue models• Conducted all laboratory activities under the regulatory requirements of the FDA, EPA, and OECD • Knowledge of sterile tissue culture techniques and maintenance of various mammalian cell lines • Generated and analyzed assay specific workbooks, data, and study reports• Generated Background Review Documents for submission to regulatory agencies• Developed the Bovine Corneal Opacity and Permeability (BCOP) Histopathology Reference Manual• Participated in the scheduling, preparation, and production of the BCOP Histopathology workshop• Prepared and reviewed SOP and equipment records in compliance with regulatory requirements

• Predicted remodeling of the left ventricle after myocardial infarctions using sonomicrometry array localization strain mapping• Determined how the reduction of left ventricular strain by mechanical unloading using a left ventricular assist device reduces infarct size and remodeling• Improved algorithm to measure areal strain, remodeling strain, circumferential strain, and longitudinal strain to correlate with echocardiographic data • Utilized the conductance catheter method to measure pressure-volume based left ventricular global function