John Melchior Email & Phone Number

Richland, WA, US

Richland, Washington, United States

I manage the Chemical Biology Team in the Biological Systems Science group at Pacific Northwest National Laboratories. Our team provides several services including synthesis of activity-based chemical probes for molecular profiling, generation of conformational-specific nanobodies to protein targets, and genetic code expansion. We complement these.

Richland, Washington, United States

I manage a diverse project portfolio with a primary focus on lipoprotein biology and development of high-throughput molecular phenotyping technologies. To this end we recently engineered a fluorescent lipoprotein profiler to profile lipoprotein subspecies in plasma and cerebrospinal fluid with unprecedented sensitivity. This will open new avenues for.

I hold a faculty joint appointment with the Department of Neurology in the School of Medicine at Oregon Health Sciences University. My research is focused on lipoproteins in the central nervous system and their role in neurodegenerative disorders such as Alzheimer's and Parkinson's Disease.

Cincinnati, OH

I hold a faculty joint appointment in the Pathology and Laboratory Medicine Department at University of Cincinnati. Our team continues to collaborate with faculty to unravel the details of lipoprotein structure and function in cardiovascular disease and diabetes.

Cincinnati Area, KY

As a postdoctoral fellow, I received conceptual and technical training in protein biochemistry under Dr. Sean Davidson, an expert in the structure/function relationships of protein moieties on lipoproteins. I mastered methodologies in protein expression and purification, size exclusion chromatography (SEC), immunoaffinify chromatography (IAC), chemical.

Doctor Of Philosophy (Ph.D.), Molecular Pathology

During my tenure at Wake Forest, I received rigorous training in lipoprotein metabolism from the late Dr. Lawrence Rudel, a world expert.

Biology

B.S.E., Mechanical Engineering