Yajun Lin Email & Phone Number

• Performing routine Protein Characterization assays, such as Intact/Reduced, Peptide Mapping, Disulfide Mapping, Free Thiol• Drafting Technical Report and assisting QA review• Operating and maintain laboratory equipment (Agilent Q-Tof; Thermo E+, QE+)• Experiencing with AUC, AAA, DSC, SEC-MS assays• Maintaining a detailed laboratory notebook (ELN) to document all experiments for QA review

Worcester, Ma

• Performed development and qualification of LC-MS/MS assays on proteins for the analysis of plasma, blood, tissue, and other biological samples to support pre-clinical PK and PK/PD studies and non-GLP toxicology studies• Extracted and analyze drugs, and biomarkers from biological samples using LC‑MS/MS techniques • Operate routine large molecule biomarker sample preparation and assay execution using TECAN• Executed sample preparation in support of proteomics investigations• Conducted small molecule mouse feces incubation using the anaerobic chamber• Performed ADC force release assay supporting pre-clinical studies• Operated and maintain laboratory equipment (AB Sciex Qtrap 4000, 6500; Triple Quad 5500)• Communicated results and data interpretation through oral presentations to other DMPK colleagues, multidisciplinary project teams, and management.• Maintained a detailed laboratory notebook (ELN) to document all experiments and findings

Greater Boston Area

• Performed testing of intermediate and final product samples to demonstrate that all products meet all standards required for cGMP operations• Performed routine and complex testing, such as enzyme activity, total protein concentration (using UV-Vis spectrophotometry Lambda 25 & DU 800), pH testing, appearance, and reconstitution, Free Thiol testing (using both UV/Vis spectrophotometry & Plate Reader) of in-process samples and final products in accordance with SOPs for product release and validation• Performed TOC testing on daily water samples, and in support of the manufacturing validation process• Reviewed and validated quality control data for compliance with procedures and specifications• Performed lab maintenance and basic equipment troubleshooting• Engaged in Spreadsheet creation, verification, and validation projects

Boston, Ma

Boston, Ma

Conducted extensive literature reviews cover issues related to the protection of human subjects in researchEngaged in 4 projects associated with the protection and the security of research data in multi-site studiesAssembled and analyzed Harvard Catalyst institutional policies associated with Investigational Drugs and Devices, Quality Assurance/Quality Improvement support, privacy, and security of health informationHelped to develop 6 brochures for Research Subject Advocacy (RSA) Program

Athens, Ohio

In the lab, we were interested in the nature compound named stevioside, specifically, the use of isosteviol in the Ugi reaction. My job was to determine if the amino acid residues on the diterpene nucleus would provide compounds with new or improved biological activities. HPLC was used to check the purity of the compounds.

Master Of Science (M.S.), Pharmaceutical Sciences, 3.5/4.0

Activities and Societies: AAPS

Bachelor Of Science (B.S.), Biochemistry, 3.3/4.0