John Randolph Email & Phone Number

Louisville, Ky, Us

Louisville, Kentucky, United States

This position involves optimizing, troubleshooting and overseeing the synthesis and purification of oligonucleotides for academic and industrial uses at both a small, high-throughput scales as well as large scales syntheses.

Montreal, Quebec, Canada

San Carlos, California, United States

ELEGEN is developing a new paradigm for the chemical synthesis of DNA, based upon a microfluidics platform that has the potential to disrupt the synthetic biology field.

Pleasanton, California, United States

This position involved:Post-PCR analysis of cleavage profiles of template- and non-template controls to guide probe design to:• Increase signal gain• Reduce baseline fluorescence• Reduce non-productive cleavage and/or incomplete cleavage of probeConception, design and testing of new high temperature fluorophore in far red channel that is approximately 6-fold brighter than existing commercially available fluorophores. (Patent application pending)Assay development of a modular system for target enrichment of rare sequences for use in the cobas® 6800/8800 systemsdNTP, primer and probe pool, and Master Mix analysesExpertise in the fields of nucleic acid chemistry, PCR, UV/Vis and fluorescence spectroscopy, RP UPLC chromatography and electrospray mass spectroscopy, 1H, 13C and 31P NMR

Sterling, Virginia, United States

This position involved:- The conceptualization, design and validation of novel new nucleotide analogs, modifiers and labeling reagents for DNA and RNA synthesis, modification, functionalization and purification.- Technical support and expertise for customers in oligonucleotide design, synthesis, deprotection, purification and analysis.- Quality Assurance including review of batch data for product release, generating original analytical reports and certificates of analysis for new products and directing investigation and resolution of customer complaints.- Expertise in the fields of nucleic acid chemistry, phosphoramidite chemistry, UV/Vis, fluorescence, and electrospray mass spectroscopy and IEX and RP HPLC chromatography.- Writing and editing articles for The Glen Report highlighting new products and applications.