Strategic role in planning and leading evidence generation initiatives to support both regulatory and market access objectives.

• Innovative medical technology product from concept to market• Clinical evidence portfolio• Market access• Regulatory clearance in multiple territories• Strategic partnerships in US, Europe, Asia

Cancer lead. I incorporate data science, image analysis and project management to deliver large international clinical trials to generate evidence supporting our new products. Novel medical imaging technologies to improve outcomes for patients with liver cancer undergoing surgery.

https://www.ucl.ac.uk/cabi/people/john-connellPost-doctoral imaging specialist at Centre for Advanced Biomedical Imaging (CABI). I am managing the installation and set up of a Bruker 9.4 Tesla preclinical MRI scanner and performing cutting edge perfusion MRI in within a variety of models including cancer, fibrosis and stem cell research.Multimodal preclinical imaging techniques such as MRI, PET and SPECT, bioluminescence and photoacoustic imaging to optimise stem cell delivery.Co-Chair of British young group of the European Society for Molecular Imaging. This group provides an easy and informal entry into the imaging community. By sharing knowledge and experiences, young scientists will be able to complement their career progression. We also communicate feedback to the society board on behalf of the young imaging scientists across Europe.Lecturer and module lead MSc Advanced Biomedical Imaging.Finnerty E et al., (2019) Noninvasive quantification of oxygen saturation in the portal and hepatic veins in healthy mice and those with colorectal liver metastases using QSM MRI. Magn Reson Med.Nahavandi P et al., (2019) Brain-wide ventricular-cerebral transport (vector) imaged by non-invasive dynamic MRI. JCBFM.Zaw-Thin M et al., (2019) Multi-modal Cell Labelling for Quantification and Optimization of Stem Cell Delivery to Orthotopic Breast Tumors. ChemrXiv.Ogunlade O, Connell JJ et al. (2017) In vivo 3-dimensional photoacoustic imaging of the renal vasculature in preclinical rodent models. Am J Physiol Renal Physiol.Scarfe et al., (2017) Preclinical imaging methods for assessing the safety and efficacy of regenerative medicine therapies. Nature Regenerative Medicine.Hsu BY et al. (2016) “pH-activatable MnO-based fluorescence and magnetic resonance bimodal nanoprobe for cancer imaging. Advanced Healthcare MaterialsConnell JJ et al. (2015) Advanced cell therapies: targeting, tracking and actuation of cells with magnetic particles. Regenerative Medicine

Permeabilisation of the blood-brain barrier at sites of cerebral metastasis.CRUK/MRC funded 4-year studentship. • Developing a novel therapeutic approach for brain cancer.• Multi-modal in-vivo imaging (MRI, SPECT, ultrasound).• Histological and molecular analysis• Analysis of results using specialised statistical and graphical software.• Sparking and managing international collaborations with industry and academia.• Presenting of internationally recognised results at conferences and in peer-reviewed journals.Publications:Connell JJ, Chatain G, Cornelissen B, Vallis KA, Hamilton A, Seymour L, Anthony DC, Sibson NR. (2013) Selective permeabilization of the blood-brain barrier at sites of metastasis. Journal of the National Cancer Institute. 105(21):1634-43. (Impact factor 15.2)Serres S, Martin CJ, Sarmiento Soto M, Bristow C, O’Brien ER, Connell JJ, Khrapitchev AA, Sibson NR. (2014) Structural and functional effects of metastases in rat brain determined by multimodal MRI. International Journal of Cancer. 134(4):885-96 (Impact factor 5.0)

'Incidence of microhaemorrhage in Alzheimer's disease model.'