John Waller Email & Phone Number

Motherwell, Scotland, United Kingdom

Sciento's tailored IT solutions cater to researchers in the Life Science sector

Utilising Visiopharm Oncotopix® and Indica Labs Halo® image analysis software our services provide detailed quantification of cells and biomarkers within brightfield and fluorescent stained histology / IHC tissue slides. We specialise in quantifying different immune cell types, cell spatial relationships and biomarker co-localisation within immuno-oncology (IO) tissue and have various published client case studies in IO and oncology. The management have extensive experience of Pharma drug discovery and our client base includes several large Pharma companies, Biotech and Academic Institutes. For more information please visit www.oraclebio.com.

Previously a senior pharmacologist and biology project leader for a total of 15 years within drug discovery units across major pharmaceutical companies with responsibility for overseeing the pharmacology of various projects delivering candidates for clinical development. Vast experience of developing in vitro, ex vivo and in vivo models across the therapeutic areas of atherosclerosis, hypertension, osteoporosis, analgesia, psoriasis and various inflammatory diseases. Expertise in PK/PD analysis, working closely with clinical exploratory development teams to generate biomarker data to feed in to clinical programs. Generated and implemented the translational biomarker strategies within pre-clinical drug discovery programs. Project manager with responsibly for managing multi-site, multi–million pound, industry/academia research programs.Specialties: Skilled in performing digital image analysis and developing various in vitro and ex vivo assays including the use of flow cytometry, ELISA, enzymology, Calcium flux, multiplex analyte detection and cell culture. Translational biology expertise with the insight to analyse PK/PD relationships and link pre-clinical and clinical data. Extensive in vivo disease model development skills. A qualified Prince2®project management practitioner.

Phd, Pharmacology

Biomedical Sciences (Pharmacology)