Jonathan Chan Email & Phone Number

- Responsible for conducting quality control testing of in-process samples, drug substances and drug products according to GMP SOPs for multiple projects simultaneously.- Project team lead responsible for tox support, release and stability testing of multiple development compounds.- Main analyst responsible for managing stability programs for commercial drug substances and products.- Leads communication and coordination with CRO; organizes meetings, testing, troubleshooting, training, finances and annual project reviews.- Presents and participates in internal and external scientific meetings.- Coordinates with multiple internal departments and external organizations to plan studies, perform testing, and troubleshoot analytical issues.- Trained multiple analysts on main analytical techniques as well as providing training sessions for multiple external labs.- Conducted analytical method validations, forced degradation studies, instrument troubleshooting and unexpected analytical result investigations.- Revised, developed, and updated SOPs as required.- Authors scientific reports and portions of Chemistry, Manufacturing, and Controls (CMC) section of regulatory filings.

-Responsible for conducting quality control testing of in-process samples, toxicology, drug substances and drug products according to GMP SOPs-Project team lead responsible for tox support, release and stability testing of development compounds-Main analyst responsible for managing stability programs for commercial drug substances and products-Presents and participates in internal and external scientific meetings and training sessions-Compiles and reviews GMP data for compliance to specification and test procedures-Revises, develops, and updates SOPs as required-Conducts analytical method qualifications/validations and analytical investigations-Authors scientific reports and portions of Chemistry, Manufacturing, and Controls (CMC) section of regulatory filings

-Responsible for conducting quality control testing of in-process samples, drug substances and drug products according to GMP SOPs-Main analyst responsible for managing stability programs for commercial drug substances and products-Compiled and reviewed GMP data for compliance to specification and test procedures-Conducted analytical method validations and unexpected analytical result investigations-Revised, developed, and updated SOPs as required

Carlsbad, Ca

-Responsible for conducting quality control testing of in-process samples, drug substances and drug products according to GMP SOPs using LC-MS, KF, and GC.-Compiled and reviewed GMP data for compliance to specification and test procedures-Conducted analytical investigations and the validation of analytical methods-Revised, developed, and updated SOPs as required

Oceanside, Ca

-Primary user of QTrap 5500, handled routine sample receiving, extraction, preparation, and analysis of drug product in various biofluids to be quantified-Method development, optimization, and validation/verification of various sample extraction and preparation procedures for analysis-Main QC analyst for primary drug product and drug substance, including annealing of single stranded siRNA, UPLC, LC-MS(ToF), Tm, HPLC, and endotoxin analysis-Writing and review of several SOPs, protocols, and method verification reports-Performed routine QC analysis on drug samples using UV/Vis spectrophotometer, KF titrator, DLS, and HPLC-Conducted solubility, drug-loading, forced degradation, and stability studies on multiple research materials/products-Created buffer, calibrated scales and pH meters weekly, and regularly updated and maintained databases on Microsoft Excel as primary point of contact

Collected depth samples from CTD casts -Performed incubations for bacterial activity with radioisotopes -Filtrated 14C-treated seawater from incubations -Worked with fluorometer to obtain chlorophyll readings -Hours per week: 35

Performed extraction of hopanols from seawater -Analysis of samples using LC/MS -DNA extraction of samples, prepping and running gel electrophoresis, running PCR -Basic LC/MS maintenance, glassware combustion, stocking chemicals -Hours per week: 20

Organized and prioritized a very demanding schedule while maintaining a 3.0 GPA - Helped creating an authentic community of people with diverse backgrounds-Worked with supervisors and other RAs to coordinate and organize resident programs-Hours per week: 20-30

Prepared and performed PCR, transformation, and transfection for gene of interest -Continued tissue culture lines for transfections and drug tests -Performed drug tests on cultured cells to determine resistance to toxicity -Cleaned and restocked lab supplies, prepped and ran gels for electrophoresis -Hours per week: 10-15