Jonathan Macdonald Email & Phone Number

New York, United States

New York, United States

Cleveland, Ohio Area

Cleveland Clinic Center for Therapeutics Discovery (C3TD)

Nashville, TN

Principal Investigator: Prof. Stephen W. FesikDiscovery of small molecule inhibitors of protein-protein interactions of WDR5- Application of structure-based design and traditional medicinal chemistry approaches to develop chemical probes and inhibitors with drug-like properties. Potency is driven by biochemical and cellular assays, while DMPK is assessed.

Sutton, Surrey

Principal Investigator: Prof. Julian BlaggThesis Title: “The design, synthesis & kinome selectivity of imidazo[4,5-b]pyridine derived fragment libraries.”- The design and synthesis of focused fragment libraries based upon the imidazo[4,5-b]pyridine scaffold- Development of direct arylation methodology to derivitize the C2-position, including experiments to.

Grimsby

Cambridge, UK

Doctor Of Philosophy (Phd), Medicinal Chemistry

Thesis: “The design, synthesis & kinome selectivity of imidazo[4,5-b]pyridine derived fragment libraries.” Funded by Cancer Research UK

Mchem, Medicinal Chemistry, 1St Class