Jose Vidal Email & Phone Number

South San Francisco, California, United States

• Executed in process testing of reagent consumables and manufacturing SOPs, work instructions, and production batch records
• Formulated buffers used to push products into final stages by applying precise pipetting techniques
• Maintained accurate, detailed documentation of batch records and notebooks under ISO regulations inside an ISO-7 cleanroom environment
• Calibrated lab equipment and troubleshooted biological/chemical reactions using analytical techniques

South San Francisco, California, United States

• Supported development, qualification, and optimization of analytical methods to characterize cell therapy drug products
• Thawed and prepared cells for seeding process used for cell line cultures with applied aseptic techniques
• Captured images of cells by light microscopy and fluorescence microscopy
• Performed cell count by NC-200 in order to check cell viability and recovery
• Maintained UPLC instrument by formulating buffers, cleaning sensors, and washing lines
• Collaborated with Discovery and Process teams to collect assay data on cell batches while providing feedback on critical targets during cell- therapeutic development and production

San Francisco, California, United States

• Performed multistep organic synthesis of therapeutic inhibitors for the channel protein CFTR in human illnesses
• Purified and characterized target inhibitors using TLC, Flash Chromatography/Biotage-Isolera (compound purification), HPLC, LCMS, and NMR
• Assigned atomic structures of compounds using proton/carbon predictors and simulators
• Reported molecular structures of target compounds using the programs Chemsketch/Chemdraw
• Organized a collection of possible target compound inhibitors of the CFTR channel protein to alleviate cystic fibrosis
• Involved in pending publication for the design of inhibitors of therapeutically relevant drug targets

Minor, Biology, General

Bachelor Of Science - Bs, Chemistry