Joseph Thibault Email & Phone Number

Greater San Diego Area

Contributed to oncology drug discovery by performing counter screens in support of ALK inhibitor lead optimization efforts. Conducted kinase compound screening (including ALK inhibitors) across many cancer cell lines to confirm genetic driven sensitivities, confirm new therapeutic indications, and nominate for in vitro assay/in vivo model development..

Greater San Diego Area

Employee of Biophase Solutions on assignment at the Genomics Institute of the Novartis Research Foundation. Conducted ubiquitin ligase target modulation studies, testing compound’s effect on protein expression and cell proliferation.

Oamishirasatomachi, Chibaken, Sanbugun, Japan

Promoted cultural exchange and mutual understanding between nations through teaching and community involvement. Independently developed and implemented energetic and exciting English lessons at both Elementary School and Jr. High School settings and facilitated English lessons and discussions for Adults. Organized and participated in various cultural.

Greater San Diego Area

Involved in identifying novel therapeutic targets associated with infectious disease. Cloned, conducted protein expression/purification, and developed assays for therapeutic targets. Conducted Ku protein stability studies using various buffer conditions. Efforts resulted in published journal article describing DNA binding assay for Ku complex drug.

Greater San Diego Area

Contributed to novel, cancer associated serine protease discovery. Cloned and characterized several novel, cancer-associated serine proteases. Conducted gene expression profiling of serine proteases on various normal/cancer cell lines and animal tumor model samples treated/not treated with Corvas developed inhibitors. Performed site directed mutagenesis of.

Greater San Diego Area

Involved in polysialyltransferase research. Characterized polysialyltransferase through the construction of deletion mutants. Genotyped mice to determine polysialyltransferase knockout status. Maintained and stocked laboratory supplies, reagents, and managed the treatment and removal of biohazardous waste for the laboratory.- Related work: Angata K, Chan.