Junjie Chen Email & Phone Number

Shanghai, China

Shanghai, China

中国 上海市

中国 北京市

Beijing City, China

- Feasibility, PSSV, SSU, SIV, SMV, QoV- Participated in CFDI inspection several times and assisted preparation

Chaoyang District, Beijing, China

· Completed systematic CRA Trainee Training by IQVIA and BeiGene· Clinical Trial Professional Domain: phase I, II and III Oncology study (China mainland and Taiwan)· Indications: ESSC, HCC, GC, B cell lymphoma etc.

Montreal, Canada Area

Graduate Student Researcher, Dr. Jean-François Côté’s Lab May. - Aug. 2018Cytoskeletal Organization and Cell Migration research unitUnderstood the role of secreted protein acidic and rich in cysteine (SPARC) protein in metastatic breast cancer cells initial survival• Studied molecular mechanism governing breast cancer metastasis• Identified SPARC expression alterations under stress conditions in different breast cancer cell lines by western blot and real-time PCR• Generated inducible SPARC-overexpressed Flp-In TRex Hela cells and HEK 293 cells by Gateway cloning technique• Explored the correlation of survival signaling pathway molecules with SPARC protein levelsGraduate Student Researcher, Dr. William Tsang’s Lab Jan. - Apr. 2018 Cell Division and Centrosome Biology research unit Investigated of the function of Centrosome protein 76 (Cep76) protein in the regulation of centriole duplication • Optimized drug treatment methods to synchronize U2OS cells into specific cell cycles verified with flow cytometry.• Studied Polo-like kinase 1 (Plk1) protein expression and activity during centriole duplication by upregulation of Cep76 with plasmid transfection and downregulation of Cep76 with siRNA.• Wrote grant proposal assignment on regulation of Cep76 protein function in centrosome duplication

Nanjing, Jiangsu, China

• Worked as an intern rotating in the Department of Surgery, Gynecology and Obstetrics, Pediatrics, and Internal Medicine• Responsible for accepting patients and in charge of them in the Inpatient Department, including asking the history of the disease, writing the medical record, performing the physical examination, diagnosing disease and giving proper medical treatment under the supervision• Assisted chief surgeons with surgeries in the Operation Room• Performed basic examinations and operations such as ECG, rhinoscopy, Fundus camera, etc. on patients in the Outpatient Department

Nanjing, Jiangsu, China

Studied the molecular mechanism of hypertension by investigation regulation of calcium channels• Explored modulation of CaV1.2 calcium channel by neuropeptide W regulates vascular myogenic tone via G protein-coupled receptor 7• Investigated effect of polypyrimidine tract binding (PTB) protein on drug sensitivity of vascular CaV1.2 calcium channel• Extracted tissues including brain, heart, aorta and superior mesenteric artery from Wistar-Kyoto and Spontaneously Hypertensive Rats model and applied western blot to identify the expression of PTB proteins in different tissues and rat models• Used real-time PCR to identify different expression and rate of CaV1.2 Exon 8 and 8a in mesenteric artery of WKY and SHR mouse models• Investigated CaV1.2 Exon 8 and 8a ratio under overexpression of PTB protein by plasmid transfection in HEK 293 cells.

Nanjing, Jiangsu, China

• Studied mechanism of Gan Han Yin medicine treatment against skin photoaging • Collected documents related to the mechanism of photoaging and its association with four specific Gan Han Yin medicines; wrote a review published in Clinical Journal of Chinese Medicine

Master Of Science - Ms, Molecular Biology / Molecular And Cellular Medicine

Bachelor Of Medicine, Bachelor Of Surgery (M.B.B.S.), Clinical Medicine

Activities and Societies: President of Youth Volunteer Association, Vice President of Nanjing Medical University Press Corps