Justin Guild Email & Phone Number
@modernatx.com
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Who is Justin Guild? Overview
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Justin Guild is listed as Undisclosed at Undisclosed, based in Cambridge, Massachusetts, United States. AeroLeads shows a work email signal at modernatx.com and a matched LinkedIn profile for Justin Guild.
Justin Guild previously worked as Senior Manager at Moderna and Manager at Moderna. Justin Guild holds Alm, Biotechnology from Harvard University.
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About Justin Guild
A Biopharmaceutical Development Expert with eighteen years of continuous experience in research and GLP labs. Utilized ever expanding skill sets in the fields of Immunology, Cellular, and Molecular Biology to support and facilitate drug discovery with a high level of competence and speed. Flexibility, excellent communication and interpersonal skills enable a high level of effectiveness both independently, and in a team, to achieve significant contributions to research and GLP preclinical assay development. Have recognized expertise with multiparameter Flow Cytometry, molecular biology, cell-based assays, ELISA and cell culture. Have advanced the development of cardiovascular, rare disease, cancer, vaccine, and type I diabetes drug candidates.
Listed skills include Assay Development, Elisa, Cell Culture, Flow Cytometry, and 28 others.
Justin Guild's current company
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Justin Guild work experience
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Senior Manager
• Expansion of duties listed under former Manager role including Bioassay Team Operational and Early Program Lead.• Continuation of cell based potency assay development, qualification and transfer activities.• Potency, cellular and molecular biology SME.
Manager
• Developed, optimized, pre-qualified and implemented multiple cell-based bioassays for lead programs• Authored method development, assay robustness, and pre-qualification reports. • Facilitated assay transfers to QC bioassay group. • Rapidly developed and implemented a cell-based protein expression bioassay for the Moderna Sars-Cov-2 vaccine. • Implemented a ribosomal engagement assay (REDA) for seasonal and/or personalized programs.
Scientist, Preclinical Pharmacology
• Lead LDLR program to key findings regarding effect of inclusion of miR recognition elements on expression, mRNA codon optimization performance, LDLR independence properties of LNPs, G6 and LNP derivatives screening. • Demonstrated a dramatic improvement in the duration of LDL-c lowering in the mouse animal model in a key PK/PD study. Demonstrated resistance to PCSK9 downregulation of PCSK9 LDLR binding mutants in vitro.• Additional five patents published during this time regarding mRNA technology (20150086614, 20150111248, 20150246139, 20150368665, 20150376648)
Principal Research Associate
• Implemented flow cytometry and ELISA based methods to successfully detect extracellular, intracellular and secreted proteins. Optimized miniaturized Western blot (Capillary Electrophoresis) method to rapidly characterize in vivo protein expression.• Five patents published during this time relating to modified polynucleotide performance and production of protein (20130259923, 20130259924, 20140010861, 20150064235, 20150064236)
Senior Research Associate
• End to end mRNA synthesis, characterization of mRNA performance, including nucleotide chemistries evaluation, in vitro, in vivo and ex vivo protein expression evaluation. • Proof of concept generation on rare disease mRNA targets.
Contract Researcher
• Successfully affinity matured an anti-EGFR single chain variable fragment (scFv) using a yeast library display system. • Ongoing application of flow cytometry and immunology expertise to optimize processes within the Merrimack Antibody Technology Team.
Senior Preclinical Associate I
• Instrumental in demonstrating that otelixizumab differentially regulates human T Regulatory and non T Regulatory T cell subsets.• Planned and executed all cellular assays pertaining to the anti-CD3 antibody program including mixed lymphocyte reaction, flow cytometry acquisition, cell sorting, and phosphoflow to further investigate and characterize the in vitro immunoregulatory properties of the company’s lead drug candidate.• Completed the majority of experiments related to the characterization of the immunoregulatory properties of anti-ILT (Ig-Like Transcript) antibodies.
In Vitro Supervisor
• Performed an extensive variety of cell culture, cytotoxicity, hematology and genetic toxicology assays in a GLP setting.• Ensured GLP and ISO compliance of the lab.
Justin Guild education
Alm, Biotechnology
H.Bsc, Bioinformatics
Frequently asked questions about Justin Guild
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What company does Justin Guild work for?
Justin Guild works for Undisclosed.
What is Justin Guild's role at Undisclosed?
Justin Guild is listed as Undisclosed at Undisclosed.
What is Justin Guild's email address?
AeroLeads has found 1 work email signal at @modernatx.com for Justin Guild at Undisclosed.
Where is Justin Guild based?
Justin Guild is based in Cambridge, Massachusetts, United States while working with Undisclosed.
What companies has Justin Guild worked for?
Justin Guild has worked for Undisclosed, Moderna, Moderna Therapeutics, Merrimack Pharmaceuticals, and Tolerx.
How can I contact Justin Guild?
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What schools did Justin Guild attend?
Justin Guild holds Alm, Biotechnology from Harvard University.
What skills is Justin Guild known for?
Justin Guild is listed with skills including Assay Development, Elisa, Cell Culture, Flow Cytometry, Immunology, Drug Discovery, Molecular Biology, and Biotechnology.
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