Joshua Wingerd Email & Phone Number

Australia

Sydney, Australia

Program Lead on multiple discovery stage projects, developing antibodies that therapeutically modulate ion channel and GPCR targets covering various therapeutic indications, such as inflammation, immunology and pain.Coordination of work across multiple global sites and with CROs, from project initiation to development candidate. Development of discovery.

Sydney, Australia

As the first employee in Sydney, I significantly contributed to establishing the AbCellera Australia site, which now employs over 50 people in a >250 sqm facility. This site was instrumental in establishing internal programs to develop antibodies that modulate complex membrane proteins, such as ion channels and GPCRs, for therapeutic purposes.I leveraged.

Sydney, New South Wales, Australia

-Hit discovery and lead generation of novel biologic therapeutics targeting a diverse ion channels pipeline.-Successful implementation of new technologies in support of ligand/voltage gated ion channel electrophysiology screening programs.

Brisbane, Australia

A Cooperative Research Centre collaborative between leading Australian research institutes, universities, and biotech companies aiming to effectively translate discovery research to clinical development of cancer therapeutics.Based at the Griffith Institute for Drug Discovery (GRIDD), the CRC team I worked with utilized a combination of in vitro.

Brisbane, Australia

An independent spinoff company from Alchemia and a continuation of previous work with an increase in CRO collaboration.High degree of autonomy. Close associations with various CROs for assay and medicinal chemistry needs. In vitro pharmacological profiling to support hit-to-lead optimisation of small molecule compounds targeting sodium channel.

Brisbane, Australia

A joint academic/biotech collaboration to develop small molecule therapeutics for the treatment of pain via targeting voltage gated ion channels. My role involved HTS and hit-to-lead selection of a dynamic small molecule synthetic library utilising a unique carbohydrate-based scaffold designed off the VAST (Versatile Assembly on Stable Templates).

Brisbane, Australia

Institute of Molecular Bioscience, University of Queensland, Brisbane, AustraliaAdvisor - Richard J. LewisDiscovery via activity guided RP-HPLC fractionation, production, NMR structural determination, and pharmacological characterization of novel peptides extracted from Cone Snail and Spider Venoms. Primary project focused on characterization of novel.

Greater San Diego Area

Developed and implemented biological assays testing novel marine natural products from algae as potential treatments for cancer and neuropathy. Maintained and developed collaborations with industry and academic partners for the purpose of expanding screening capabilities and compound libraries as well as developing compounds for future therapeutics.Further.

Greater San Diego Area

Worked as part of the Ion Channels R&D team to develop, validate and implement cell-based voltage gated ion channel assays for transfer to HTS. Primary responsibilities included assay development using fluorescent reporters of ion flux or membrane potential changes on a FLIPR and eVIPR (proprietary equipment for electric field stimulation, EFS), or.

San Diego State University

Primary focus on protein mediated cell-signaling cascades affecting cardiac apoptosis and degeneration post infarction or related to cardiomyopathy. Used a variety of molecular biology and immuno-fluorescent imaging methods to determine specific activity of signaling proteins in cardiac apoptosis models.

Phd, Neuropharmacology Of Venom Peptides Targeting Nav Channels

Activities and Societies: 2009-2012 -- Australian Society for Biochemistry and Molecular Biology 2010-2013 -- The Australasian Society of.

B.Sc., Cell And Molecular Biology