Kaitlin Hamilton, Ph.D. Email & Phone Number

Columbus, Ohio, United States

I am a scientist on the Protein-Based Assays team within the Analytical Development group at Forge Biologics. I supervise a team of two associate scientists. My day-to-day tasks are to:• Develop and optimize protein-based assays to evaluate gene therapy vectors• Communicate assay development progress in internal reports and presentations• Prepare methods and forms to document assay protocols• Perform testing on in-house and client samples to provide data for ongoing… Show more I am a scientist on the Protein-Based Assays team within the Analytical Development group at Forge Biologics. I supervise a team of two associate scientists. My day-to-day tasks are to:• Develop and optimize protein-based assays to evaluate gene therapy vectors• Communicate assay development progress in internal reports and presentations• Prepare methods and forms to document assay protocols• Perform testing on in-house and client samples to provide data for ongoing projects• Meet with my team weekly to discuss assay development progress and to analyze and interpret data• Train team members to perform protein-based assays to facilitate method transfer between departments Show less

Columbus, Ohio, United States

I am a scientist on the Protein-Based Assays team within the Analytical Development group at Forge Biologics. My day-to-day tasks are to:• Develop and optimize protein-based assays to evaluate gene therapy vectors• Communicate assay development progress in internal reports and presentations• Prepare methods and forms to document assay protocols• Perform testing on in-house and client samples to provide data for ongoing projects• Train team members to perform… Show more I am a scientist on the Protein-Based Assays team within the Analytical Development group at Forge Biologics. My day-to-day tasks are to:• Develop and optimize protein-based assays to evaluate gene therapy vectors• Communicate assay development progress in internal reports and presentations• Prepare methods and forms to document assay protocols• Perform testing on in-house and client samples to provide data for ongoing projects• Train team members to perform protein-based assays to facilitate method transfer between departments Show less

Columbus, Ohio

I worked on my doctoral dissertation in the lab of Dr. Amal Amer in the Department of Microbial Infection and Immunity in the College of Medicine. My day-to-day tasks were to:• Investigate mitochondrial dysfunction to evaluate its contribution to macrophage dysfunction in a mouse model of cystic fibrosis• Develop new protocols for the Amer Lab to study aspects of mitochondrial function, including oxygen consumption, reactive oxygen species production, membrane potential, ATP… Show more I worked on my doctoral dissertation in the lab of Dr. Amal Amer in the Department of Microbial Infection and Immunity in the College of Medicine. My day-to-day tasks were to:• Investigate mitochondrial dysfunction to evaluate its contribution to macrophage dysfunction in a mouse model of cystic fibrosis• Develop new protocols for the Amer Lab to study aspects of mitochondrial function, including oxygen consumption, reactive oxygen species production, membrane potential, ATP production, and mitophagy• Collaborate with mitochondrial biology experts to learn new techniques and discuss data analysis• Communicate with advisor to discuss project progress in weekly meetings• Prepare manuscripts and conference presentations to disseminate results• Teach lab protocols to new and current lab members to provide them with the technical skills needed for their individual projectsDuring my time in the Amer Lab, I presented at 18+ local and national science conferences to audiences ranging from the general public to specialized experts. This included invitations to speak at the 2018 North American Cystic Fibrosis Conference in the "Airway Innate Defense Defects" workshop and at several Cure Cystic Fibrosis Columbus meetings. I also successfully competed for three research trainee grants, including an NIH T32 grant. Show less

Pittsburgh, Pennsylvania

I worked as an undergraduate research assistant in the lab of Dr. Alex Evilevitch in the Department of Physics in the Mellon College of Science. My day-to-day tasks were to:• Characterize the physical mechanisms controlling the viral infection process to inform the design of new antiviral treatments• Coordinate with graduate students to assist with plaque assays to study bacteriophage infection and with atomic force microscopy to study herpesvirus capsid stability•… Show more I worked as an undergraduate research assistant in the lab of Dr. Alex Evilevitch in the Department of Physics in the Mellon College of Science. My day-to-day tasks were to:• Characterize the physical mechanisms controlling the viral infection process to inform the design of new antiviral treatments• Coordinate with graduate students to assist with plaque assays to study bacteriophage infection and with atomic force microscopy to study herpesvirus capsid stability• Communicate with advisor in monthly lab meetings to discuss progress• Prepare conference presentation to disseminate resultsI presented my work in the Evilevitch Lab at the 2015 Meeting of the Minds, which is Carnegie Mellon's annual student research symposium. Show less

Columbus, Ohio

I worked as a summer undergraduate research intern in the lab of Dr. Li Wu in the Department of Veterinary Biosciences. My day-to-day tasks were to:• Analyzed the role of SAMHD1, a retroviral restriction factor, in regulating innate immune signaling to inform the design of new antiviral treatments for HIV• Performed immunoprecipitation and immunoblotting to confirm SAMHD1’s interaction with MAL, a protein that associates with TLR-4 to initiate an innate immune response•… Show more I worked as a summer undergraduate research intern in the lab of Dr. Li Wu in the Department of Veterinary Biosciences. My day-to-day tasks were to:• Analyzed the role of SAMHD1, a retroviral restriction factor, in regulating innate immune signaling to inform the design of new antiviral treatments for HIV• Performed immunoprecipitation and immunoblotting to confirm SAMHD1’s interaction with MAL, a protein that associates with TLR-4 to initiate an innate immune response• Communicated with advisor and lab members in weekly lab meetings to discuss progress• Prepared conference presentation to disseminate resultsI presented my work in the Wu Lab at the 2014 Summer Research Opportunities Program Symposium held at The Ohio State University. Show less

Doctor Of Philosophy (Ph.D.), Molecular, Cellular, And Developmental Biology

Activities and Societies: Department of Microbial Infection and Immunity's Education and Curriculum Committee; Sigma Xi Science Fair.

Bachelor’S Degree, Biological Sciences

Activities and Societies: Biological Sciences Student Advisory Council; Mellon College of Science Mentors Program; Biological Sciences.