Katherine Lowe Email & Phone Number

San Francisco, Ca, Us

Menlo Park, Ca

Emeryville, Ca

• Manufactured and dispensed materials for non-clinical studies using the company's proprietary microfluidic-based platform for RNA-based therapeutics• Tracked manufacturing process and equipment performance by recording deviations and discrepancies to drive process improvements• Investigated root causes of deviations and troubleshooted issues related to the software and hardware of the equipment to set preventative measures• Implemented process improvements and contributed to product support documentation such as batch records, standard operating procedures, user requirement specifications, and protocols• Coordinated with R&D, Engineering, Quality, and Process Development teams to execute manufacturing process studies• Supported the development of the vial filling station within the company's GMP facility by communicating with outside vendors to procure pump equipment and single-use consumables

San Diego, Ca

• Worked within the fluidics team to help launch the NextSeq 1000/2000 sequencing platforms• Familiar with troubleshooting issues related to hardware, software, and firmware on test fixtures and sequencers• Involved with the development of reagents and consumable kits, authoring reports related to critical parameter management and engineering verification testing to document the robustness of consumables• Performed quality and reliability tests on reagent cartridges used in sequencing, utilizing MATLAB and Python scripts to process data from fluidics testing

Altman Clinical And Translational Research Institute, Ucsd

Principal Investigator: Dr. Elliot McVeighCardiovascular Imaging Lab• Characterized the average velocity of coronary vessels from angiograms using MATLAB to obtain accurate vessel geometry and to provide a more accurate diagnosis of coronary lesions• Reconstructed 3D models of the left atrium and ventricle from CT images in order to help develop a deep neural network so that these models can be made automatically in the future• Segmented the left atrial appendage (LAA) of the heart in CT images from multiple patients to develop more efficient method of identifying the LAA

Science And Engineering Research Facility, Ucsd

Principal Investigator: Dr. Stephanie I. FraleyVascular Mimicry Senior Design Team• Created a fluidic device within a cross-functional team for the purpose of studying cancer cell and endothelial cell interactions to further understand the mechanisms of cancer metastasis and to provide future applications in diagnostics and personalized treatments• Designed the mold for device fabrication in Autodesk Inventor• Modeled fluid flow in ANSYS to determine ideal pressure gradients to apply to the device through FEA

Science And Engineering Research Facility, Ucsd

Principal Investigator: Dr. Peter Yingxiao WangMentor: Dr. Kathy LuMolecular Engineering for Cellular Imaging and Reprogramming Lab• Assisted with developing live-cell imaging software called Fluocell, using MATLAB and Java, with the purpose of allowing more efficient quantitative analysis• Made Fluocell more user-friendly by editing the user’s guide and reformatting the main graphic interface• Modeled the epidermal growth factor receptor system using ODEs in MATLAB

Bethesda, Md

Principal Investigator: Dr. Ajay ChitnisNeural Developmental Dynamics Lab• Restored hair cell formation in mutant zebrafish embryos by ectopically expressing the gene atoh1a• Programmed computer model, using NetLogo, of posterior lateral line primordium in zebrafish in order to analyze the factors that affect the primordium’s growth

Master Of Translational Medicine

Master Of Translational Medicine

Bachelor Of Science (B.S.), Bioengineering

Activities and Societies: Biomedical Engineering Society - Vice President Internal (2017-2018) & Outreach Committee Chair (2016-2017)