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I am currently serving as a creative consultant for a consulting group. This company provides design and strategic assistance for organizations facing challenging automation, biotechnology, general innovation, and design obstacles. Prior to 2011, I served as Director of Process Design and Research at Biolex Therapeutics, Inc. where I designed, and developed their upstream Bioproduction process. This project was challenging and engaging on many levels, the most serious being-- this kind of bio-pharmaceutical production system had never been successfully created before. The resulting system has been referred to as a "game changing" and "disruptive" approach to difficult molecule manufacturing*. I patented and developed this technology among others during my tenure at Biolex. The process was later purchase by Synthon Pharmaceuticals and is currently being studied for application as a production platform for Synthon's therapeutic molecules. While working at Biolex prior to 2005, I led their automation development team as Director of Automation. In this position, I created a completely automated novel plant tissue culture system. The critical development that allowed the system to succeed was a novel micro plate that accomplished renewal of culture media without tissue transfer. Additionally, the system employed integrated CCD camera-based tissue evaluation, allowing researchers to manage and harvest their experiments remotely. I have designed a wide variety of successful hardware, automation, and process solutions during my career. The previous examples are just a sampling of the novel systems and hardware that I have created in response to difficult and seemingly insurmountable research and development problems. I've had a widely varied career; problem solving in numerous types of tech projects across numerous disciplines and continue this legacy at my current position.(*General Discussion at the BPI Summit Symposium, Durham, NC, November 2008.)Specialties: Cross functional innovation solutions; Laboratory robotics; plant-based pharmaceutical bioproduction; aquaculture system design and automation; single use hardware and system design; automated laboratory research hardware and process design, aseptic process automation and design; conceptual and strategic ideation; tech transfer; CAD design and hardware problem solving; business intelligence and IP analysis
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Director Of Process Design And ResearchBiolex Therapeutics, Inc. Jan 2005 - Dec 2011Pittsboro, NcDesigned, developed, and implemented 2 successful plant-based bio-pharmaceutical production systems; one being reusable and based on clean-in-place technology; and the other being based entirely on our proprietary single-use technologies. These upstream process projects were designed to provide a scalable pharmaceutical-grade manufacturing system for application to a highly productive, epipelagic, aquatic plant culture (Lemna minor). I acted as team lead for the group that created and tested all upstream designs including those related to MPB, bioproduction, scale-up, culturing, harvest and biomass sequestration. Directed the development of the industrialized version conforming to GMP and USP requirements and assisted with QA guideline development/implementation. These designs now include issued patents and patent applications currently in process. (For a full description of the SU process, see the publication listing below.) This particular project and its side projects were engaging; more so due to the inherent complexity and the lack of any prior art or comparable systems. Once the development projects were successfully completed, I then provided SME assistance, further scale-up design and integration consulting for the GMP installation.
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Director Of AutomationBiolex Therapeutics, Inc Jan 2000 - Jan 2005Responsible for creation of a novel automated plant based high-throughput screening system based on a modified TECAN liquid handler platform. Created a novel automated plant growth maintenance system used for screening and propagating the plant-based (Lemna sp.) production platform. Modified and programmed liquid handlers for use in asymmetric processes for non-standard applications as required for the Lemna sp. platform. Designed additional hardware not available OTS--as well, I was responsible for the conception, design, and fabrication of preliminary upstream production prototypes. Served as a member of the Biolex Executive Committee.
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Senior Project EngineerGlaxowellcome Jan 1996 - Jan 2000Directed 12 engineers and was directly responsible for GMP compliance of analytical and development instrumentation for all RTP campuses in and around the Moore Drive Facility. Consulted on R&D automation projects and process design projects. Conceived, developed, and implemented tech transfer education program, HPLC operation techniques course, electronics basics for technical resources. -
President And Senior EngineerAlphatech Research Services Jan 1994 - Jan 2000Created and operated a private consulting firm primary assisting government and private laboratories with automation and equipment related issues. Consulted as an instrument broker and a process design consultant. Intellectual Property and Publications Issued Patents (does not include foreign patents):
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Adjunct Assistant ProfessorDuke University Aug 1995 - Dec 1995Durham, NcCo-lecturer for a business ethics course addressing ethics and morality in technologically complex world.
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Director, Molecular Genetics Core FacilityNorth Carolina State University Genetics Department Jan 1984 - Apr 1994Set up and operated a university wide core facility providing analytical and prepartive HPLC services, DNA/RNA oligonucleotide synthesis services, instrumentation engineering, fluorescent spectroscopy, Scientific illustration.
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Frequently Asked Questions about Keith Everett
What is Keith Everett's role at the current company?
Keith Everett's current role is Innovation, Biotech Hardware and Process Design.
What is Keith Everett's email address?
Keith Everett's email address is ke****@****lex.com
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Keith Everett's direct phone number is +191954*****
What are some of Keith Everett's interests?
Keith Everett has interest in Social Services, Uav Control And Aerodynamics, Disruptive Technologies, Economic Empowerment, Anthropology, Politics, Solidworks Cad, Education, Environment, Cad Based Problem Solving.
What skills is Keith Everett known for?
Keith Everett has skills like Technical Transfer Managment And Consulting, Design For Manufacturing, Manufacturing, Problem Solving, Gmp, Technology Transfer, Biotechnology, Medical Devices, Product Development, Quality Assurance, Molecular Biology, Hardware And Process Design And Documentation.
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