Kyle Bolduc Email & Phone Number

Ludwigshafen, De

Working with a highly motivated project team and interacting with a large group of stakeholders and a global business team to deliver innovative and sustainable solutions. Driving profitability through identification and achievement of customer and market development opportunities, and initiation of key technical projects and developments, as well as driving results as an active member of the Customer Network Team and through strong collaboration with other organizational functions globally. Defining specific activities and timelines in alignment with the Team to ensure successful and timely implementation of agreed measures to generate new business for BASF globally, and serve as internal and external point person for identified new business development projects.

Ludwigshafen, De

Lead on formulation optimization of first-to-market rodenticide Selontra® for US market. Initiated collaboration with manufacturing site QA in equipment modernization and training initiatives for process efficiencies and cost savings. Provided technical know-how for the strategic development of termite control products, and for identification of Fendona™ CS unique value propositions to promote launch. Built analytics laboratory to support long-term growth of innovative non-crop product offerings. Method development on 11 global pest control products with emphasis on transferability to manufacturing site for scale-up at pilot plant. Motivation, mentoring, and professional development of 1 indirect report (Research Associate I) and 3 temporary direct reports (Summer Interns).

Client-focused design and development of discovery formulations for therapeutics in both small molecule and antibody-drug conjugate (ADC) spaces. Special emphasis on challenging oral formulations, including solubility and permeability enhancement, solid form characterization, bioavailability assessment, and simulated metabolism. Nanoparticle and nano-encapsulation methods for protein and small molecule formulation and extended release. Extensive analytical method development and qualification adhering to GLP and GMP standards. Project Manager for the implementation of a comprehensive technical operations system to streamline client services and improve internal efficiency.

Chicago, Illinois, Us

Develop technology landscapes for clients seeking disruptive innovation. Connect Fortune 500 companies to emerging research in academia and at start-ups to address technical challenges and build advisory boards.

Ann Arbor, Michigan, Us

Design and chemoenzymatic synthesis of novel anticancer cryptophycin natural products with a special emphasis on improved pharmacokinetics. Development and optimization of thioesterase (CrpTE) and P450 epoxidase (CrpE) domains for enzymatic assembly. Mentored one graduate and two undergraduate students to significant advancements in cryptophycin biochemistry and analogue design.

Durham, North Carolina, Us

Critical review and correction of grammar, punctuation, and language issues to help more than 570 scientific manuscripts reach publication. Conferenced with management to improve editor bonus structure and streamline the submission and review process.

Jersey City, New Jersey, Us

Synthesized and characterized chemical hits for activity against human protozoan parasite. Advanced promising family of chemical compounds to lead optimization for Human African Trypanosomiasis (African sleeping sickness). Supported group functions for data collection and presentation to DNDi representatives.

Conducted quality control analysis on known and novel vaccine substance and product. Organized and presented results to vaccine development team on regular intervals.

Durham, North Carolina, Us

Established efficient and stereoselective basis for the total synthesis of the immunosuppressive and osteogenic natural products subglutinols A and B. Managed ordering and safety for a laboratory of 5 researchers.

Ann Arbor, Michigan, Us

Screened single gene overexpression library of yeast to elucidate biochemical pathways of cadmium toxicity.

Ann Arbor, Michigan, Us

(UROP student, September to April only) Optimized capillary electrophoresis conditions for the separation of superoxide dismutase (SOD) mutants. Isolated inorganic zinc complexes for structural analysis by ZANES and XAFS.

Ann Arbor, Mi, Us

Synthesized and purified commercial products and intermediates ranging from small, drug-like heterocycles to more complex biological signalers involved in inflammation, metabolism, and epigenetics.

Doctor Of Philosophy (Ph.D.), Medicinal And Pharmaceutical Chemistry

Master Of Science (M.S.), Organic Chemistry

Bachelor Of Science In Chemistry, Majors In Chemistry And Biochemistry