Laura Gonzalez-Malerva Email & Phone Number

Salt Lake City, Ut, Us

Salt Lake City, Utah, United States

Salt Lake City Metropolitan Area

Greater Salt Lake City Area

Support production of clinical testing through variant review, curation, and quality control.Utilize in-house software tools to generate customized reports.Troubleshoot complex cases and support the clinical production laboratory.Help guide the bioinformatics team members in building clinically relevant and biologically informed systems and processes.

Clinical Support Center

Provide accurate and timely actionable genomic variant assessment according to the ACMG and AMP guidelines for somatic and inherited clinical interpretation. Preparation of patient’s clinical reports for final evaluation of Directors, which contain clinically significant variants, FDA drugs approved and clinical trials. Collaborate with bioinformatics team to validate, implement and continually improve the genomic variant knowledge database developed in house to generate an automated report.

445 North 5Th Street Phoenix, Az 85004

Clinical curation scientist responsible for accurately identifying and classifying actionable genomic variants detected by a clinical genomic test. At Ashion®, we provide personalized options for today’s cancer treatment.Ashion® is a CAP accredited and CLIA-certified clinical genomics testing laboratory committed to accelerating the adoption of precision medicine in mainstream oncology, leveraging years of scientific and clinical experience. We offer a wide range of testing capabilities to assist our Physicians, Health Systems, Research and Commercial partners to provide precision cancer treatments.

Mesa, Az.

Coordinate and organize monthly events for members, resulting in a fast growing chapter.

Tempe, Az. Usa

‒ Led the Breast Cancer Project by implementing several cell based screening assays (cell migration, invasion, anoikis, proliferation, apoptosis and 3D cultures) to characterize phenotypic differences in several TP53 mutant stable mammary cell lines to identify targetable pathways. ‒ Development of grant proposals and progress reports. Experience in searching for prospective grants, development of the research idea and submission of the application. Executed the proposal application and wrote reports of results obtained when successfully awarded. ‒ Presented status reports, progress on projects to supervisor, collaborators and colleagues in meetings and conferences.‒ Supervised collaborative projects; ensured timeline, tasks and goals compliance and accurate data transfer. ‒ Broad expertise in culture of mammalian cells from primary tissue and development of stable transduced cell lines.‒ Scientist reviewer for the Breast Cancer Research Program (BCRP) at the Department of Defense, U.S. Army Medical Research and Material Command.

Tempe, Az. Usa

‒ Identified and characterized a protein that is involved in autophagy and contributed to tamoxifen resistance using high-throughput kinases screen. ‒ Genomic, proteomic and transcriptomic analysis of tamoxifen sensitive and resistant breast cancer sub-clones. ‒ Assisted the principal investigator on peer review manuscripts from scientific journals.

Greater Boston Area

‒ Identified a signature of genes that are relevant for tamoxifen resistance using transcriptomic analysis of tamoxifen sensitive and resistant breast cancer sub-clones. ‒ Implemented sub-cloned cell line models that are sensitive or resistant to clinical drugs. ‒ Drafted requests for grant proposals and progress reports. ‒ Presented status reports, progress on projects to supervisor and collaborators.

Mexico City Area, Mexico

‒ Taught principles of cell biology, cytoskeleton and proteomic courses.‒ Trained medical and biology students on various proteomics techniques used in basic research science.

Mexico City Area, Mexico

‒ General procedures for the development of new biological products.

Phd; Bs, Biomedical Sciences; Biological Chemistry And Pharmacology, Phd

Dissertation: Muscular Myosin Isoforms of Taenia solium (Cestoda). 2004

Bachelor'S Degree, Chemistry And Pharmaco-Biology