Qirun Li Email & Phone Number

Boston, Massachusetts, United States

Commercial Manufacturing, Continuous Process Verification

Norwood, Massachusetts, United States

· Executing fill finish manufacturing activities in cleanroom with both master batch records and electronic manufacturing execution systems (MES) for rapid disposition of clinical drug products. · Performing reviews and facilitating corrections of manufacturing records generated from fill finish manufacturing activities, including compounding, sterile.

Pittsburgh, Pennsylvania, United States

• Synthesized polymeric compounds for plant foliar drug delivery.
• Characterized cellulose samples using NMR, SEM, EDS, XRD, GPC, Raman Spectroscopy, SLS, DLS.
• Fabricated cellulose thin film on silicon wafers and QCM disks using spinning coating processes.
• Maintained a chemical inventory for polymer extraction and characterization.

Pittsburgh, Pennsylvania, United States

• Managed laboratory equipment for chemical engineering operations laboratory courses.
• Supervised undergraduate chemical engineering students in industrial unit operations laboratory environment.
• Revised students’ experimental plan for both routine operations and open-ended student-led final project.

Newark, Delaware, United States

• Supervised students in organic chemistry and general chemistry laboratory courses for life sciences majors.
• Facilitated laboratory procedures improvements ensuring safety while streamlining the lab curriculum.
• Held office hours and special review sessions for students across the chemistry and biochemistry department.
• Evaluated students’ assignments and assisted in novel comprehensive assessments design and implementation.

Newark, Delaware, United States

• Designed fluorescent protein drug delivery platforms featuring rapid incorporation of therapeutic enzymes, clustering of tumor-targeting peptides, and pH-responsive endosomolytic peptides.
• Expressed recombinant proteins in bacterial and mammalian expression systems, utilizing biochemical engineering techniques including unnatural amino acids incorporation via amber stop codon suppression, automatic.
• Synthesized tumor-targeting peptides using solid state peptide synthesizer for incorporating reactive handles enabling spatial controlled incorporation of peptides onto surface of recombinant protein constructs.
• Delivered chemically decorated protein constructs into mammalian cell culture for evaluation of protein uptake, determination intracellular trafficking routes, and validation of protein constructs reaching specific.
• Purified synthesized functional peptides using HPLC systems, and chemically modified proteins using affinity chromatography, size exclusion chromatography, and heat shock.
• Constructed DNA plasmids using restriction enzymes for fusion protein designs, enabling endosomal escape under acidic conditions.

Newark, Delaware, United States

• Synthesized functionalized unnatural amino acids for different applications in protein and peptide engineering, including 19F NMR detection, bio-orthogonal reactions, conformational control, and controlling fluorescent.
• Purified synthesis products through preparative chromatography, manual and automatic column chromatography, and thin layer chromatography.
• Constructed short peptides via manual cycles of solid-state peptide synthesis and purified the products on HPLC.
• Obtained, processed, and interpreted experimental data of synthesis compounds analysis from NMR Spectroscopy and Mass Spectroscopy.

Newark, Delaware, United States

• Designed and tested new laboratory procedures for introduction of application-focused experiments into integrated chemistry and biology curriculum for life sciences majors.
• Proctored exams and graded assignments, quizzes, and exams, and provided constructive feedback to students.

Newark, Delaware, United States

· Shadowed post-doc researcher performing organic synthesis and polymer characterization.· Extracted active components in Curcuma zedoaria using various solvents and methods.· Purified and studied extracted C. zedoaria compounds in inflammatory breast cancer cells models. · Evaluated compounds potency via cell viability assays in various mammalian cell.

Honors Bachelor Of Science In Engineering With Distinction, Chemical Engineering

Activities and Societies: Minors in Biochemical Engineering, Material Science and Technology, Chemistry. Honors Thesis: Histone Mimetic.

Honors Bachelor Of Science, Biochemistry

Activities and Societies: Minors in Biochemical Engineering, Material Science and Engineering, Chemistry.

Chemical Engineering

High School Diploma