Mackenzie Thorpe Email & Phone Number

San Diego, California, United States

San Diego, California, United States

San Diego, California, United States

• Managed and coordinated the execution of lab performance tests for more than 2,000 samples to provide guidance for the selection of an optimal, custom sample collection tube and buffer
• Led a cross functional team in PDP project to develop and validate a manual and automated process to perform cWGS on the Illumina NovaSeq with a 15-day total turnaround time
• Authored PDP and development documentation in an electronic quality management system
• Managed project milestones and actively communicated timelines to stakeholders and senior management
• Led cross-functional development team that executed DOE’s to create a process to sequence on the Illumina NovaSeq
• Collaborated with R&D and automation teams to create a process to sequence and troubleshoot sequencing runs

San Diego, CA

• Participate in process sustaining, definition and improvement, design, development and quality test activities sequencing whole human genomes in a clinically regulated and CAP/CLIA certified environment.
• Troubleshoot production line issues related to yield, quality and throughput.
• Construct and execute controlled experiments (including DOE's) to optimize processes, address yield and quality issues and drive implementation of solutions in a production environment to meet production goals.
• Analyze process test results, issue reports and make technical recommendations.
• Work cross functionally with R&D, Manufacturing and Quality to develop processes for new sequencing and genotyping services and improve processes of existing services

• Operate Illumina sequencing equipment in a high throughput, fast-paced and CLIA regulated environment
• Troubleshoot production line issues related to yield, quality and throughput by monitoring instrument quality data
• Ensure proper maintenance of equipment and adherence to SOPs
• Provide reports as necessary for all new development testing, while tracking and reporting all lab incidents to laboratory supervisor
• Keep lab stocked of appropriate reagents and materials

Berkeley, CA

• Assisted graduate student with the project of a mobile protein structure that harnesses the mechanical energy of ATPase
• Conducted assays to acquire and analyze Michaelis-Menten kinetics for the ATPase enzyme
• Grew Escherichia coli cultures to acquire proteins of interest, including His-Tag and Strep-Tag Gamma Prefoldin
• Utilized fast protein liquid chromatography (FPLC), ion-exchange chromatography and gel electrophoresis in protein purification

Berkeley, CA

• Developed relevant discussion topics and practice problems to present to students in a small, classroom setting
• Facilitated the discussion of problematic topics among students
• Collaborated with other teaching instructors during weekly meetings to assess and improve instructional methods
• Prepared students for lecture by presenting new and difficult material ahead of the pace of lecture

Berkeley, CA

• Assisted a graduate student with organic chemistry reactions involving the use of new gold catalysts
• Designed experiments to test applicability of gold catalysts in [2+2] cycloaddition reactions
• Implemented organic chemistry purification and separation techniques (column/flash chromatography, extractions, etc.)
• Researched known chemistry and used this knowledge to develop possible experiments
• Analyzed chemical data made during new and repeated experiments via NMR and TLC

Bachelor'S Degree, Chemical Engineering, 3.94 Gpa

Activities and Societies: American Institute of Chemical Engineers (AIChE) Member Tennis at Cal Member

Education record