Madeleine Murphy

Madeleine Murphy Email and Phone Number

Computational Associate II at the Broad Institute of MIT and Harvard @ Broad Institute of MIT and Harvard
cambridge, massachusetts, united states
Madeleine Murphy's Location
Cambridge, Massachusetts, United States, United States
Madeleine Murphy's Contact Details

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About Madeleine Murphy

I am currently working as a Computational Associate II in the Lander Lab/Jones Group at the Broad Institute of MIT and Harvard. I am passionate about using my skills as a computational biologist and the developing technologies in machine learning and AI for positive impacts on our environment and human health.I graduated from UCLA as a departmental scholar with an M.S. in Bioinformatics and a B.S. in Computational and Systems Biology. Special interests include machine learning & statistics, genetics, molecular biology, data-driven modeling, climate change, systems biology, and immunology.

Madeleine Murphy's Current Company Details
Broad Institute of MIT and Harvard

Broad Institute Of Mit And Harvard

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Computational Associate II at the Broad Institute of MIT and Harvard
cambridge, massachusetts, united states
Employees:
2585
Madeleine Murphy Work Experience Details
  • Broad Institute Of Mit And Harvard
    Computational Associate Ii
    Broad Institute Of Mit And Harvard Jun 2024 - Present
    Cambridge, Massachusetts, United States
  • Broad Institute Of Mit And Harvard
    Computational Associate I
    Broad Institute Of Mit And Harvard Aug 2022 - Jun 2024
    Cambridge, Massachusetts, United States
    As part of the Lander Lab and Novo Nordisk Foundation Center (NNFC), tackled multiple projects with a general focus on better understanding the genome through cellular models, for example:* Analyzed perturb (CRIPSRi) and base-edited single-cell RNA and ATAC-seq datasets in IPSCs, hepatocytes, and neuronal cells using existing statistical methods as well as novel regressions for detecting changes in gene expression.* Implemented multiple analysis pipelines ranging from eQTL detection and… Show more As part of the Lander Lab and Novo Nordisk Foundation Center (NNFC), tackled multiple projects with a general focus on better understanding the genome through cellular models, for example:* Analyzed perturb (CRIPSRi) and base-edited single-cell RNA and ATAC-seq datasets in IPSCs, hepatocytes, and neuronal cells using existing statistical methods as well as novel regressions for detecting changes in gene expression.* Implemented multiple analysis pipelines ranging from eQTL detection and annotation to parallelized donor assignment in cellular village data.I have also led workshops, presented posters at multiple conferences (NNFC Symposium, Oct 2023, and Broad Retreat, Dec 2023), and served on a panel at EMBL-EBI's program "Best practice for perturb-seq data analysis and integration", alongside leading PIs in the field. Show less
  • Ucla Department Of Bioengineering
    Student Researcher
    Ucla Department Of Bioengineering Jan 2020 - Jun 2022
    Los Angeles, California, United States
    The Meyer Lab at UCLA• Developed tensor decomposition method (in broader dimensionality reduction class) capable of handling longitudinal sample data. Master's thesis: "Continuous Tensor Factorization Effectively Reduces Data with Longitudinal Measurements" (https://escholarship.org/uc/item/45m3s58s).• Investigated tensor factorization approaches for the study of systems serology data collected from HIV and COVID-19 patients, with the goal of predicting protective immunity in patients… Show more The Meyer Lab at UCLA• Developed tensor decomposition method (in broader dimensionality reduction class) capable of handling longitudinal sample data. Master's thesis: "Continuous Tensor Factorization Effectively Reduces Data with Longitudinal Measurements" (https://escholarship.org/uc/item/45m3s58s).• Investigated tensor factorization approaches for the study of systems serology data collected from HIV and COVID-19 patients, with the goal of predicting protective immunity in patients to aid the development of vaccines. Research led to second authorship on paper: "Tensor‐structured decomposition improves systems serology analysis" doi: 10.15252/msb.202110243• Hired as a full-time undergraduate researcher for the Summer of 2020.Data analysis done in Python and Julia, and managed through GitHub. Show less
  • Ideaya Biosciences
    Bioinformatics Intern
    Ideaya Biosciences Jun 2021 - Sep 2021
    San Francisco Bay Area
    • Utilized machine learning techniques to investigate synthetic lethality interactions that indicate possible therapeutic targets in patients with cancer. • Implemented statistical methods for hypothesis testing; worked with DepMap data.
  • Ucla Athletics
    Peer Learning Facilitator, Academic & Student Services
    Ucla Athletics Sep 2019 - Jun 2021
    Greater Los Angeles Area
    Peer tutor. Facilitate UCLA students in their understanding of class materials in various subjects. Main subjects taught include Differential and Integral Single Variable Calculus, Integration and Infinite Series, Multivariable Calculus, Differential Equations, and Genetics, Evolution, and Ecology.
  • Ucla Southern Regional Library Facility
    Student Assistant
    Ucla Southern Regional Library Facility Jan 2018 - Jun 2019
    Greater Los Angeles Area
  • Sequoyah Country Club
    Lifeguard And Swim Instructor
    Sequoyah Country Club May 2017 - Sep 2017
    Oakland, Ca
  • Oakland Hills Tennis Club
    Lifeguard
    Oakland Hills Tennis Club May 2014 - Sep 2017
    Oakland, Ca

Madeleine Murphy Education Details

Frequently Asked Questions about Madeleine Murphy

What company does Madeleine Murphy work for?

Madeleine Murphy works for Broad Institute Of Mit And Harvard

What is Madeleine Murphy's role at the current company?

Madeleine Murphy's current role is Computational Associate II at the Broad Institute of MIT and Harvard.

What is Madeleine Murphy's email address?

Madeleine Murphy's email address is mm****@****ute.org

What schools did Madeleine Murphy attend?

Madeleine Murphy attended University Of California, Los Angeles, University Of California, Los Angeles, Bishop O'dowd High School.

Who are Madeleine Murphy's colleagues?

Madeleine Murphy's colleagues are Sonia Bolshakova, Joana Quintal, Mba, Cmp, Cassidy Cox, Keith Rivera, Chyna Betts, Anurag Sodhi, Anton Kovalsky.

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