Mahmoud Mahmoudian, Phd, Frs

Mahmoud Mahmoudian, Phd, Frs Email and Phone Number

General Partner, Chief Investment Officer @ Summit Impact Partners
Cambridge, MA, US
Mahmoud Mahmoudian, Phd, Frs's Location
Cambridge, Massachusetts, United States, United States
Mahmoud Mahmoudian, Phd, Frs's Contact Details

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About Mahmoud Mahmoudian, Phd, Frs

Chief Executive Officer, Director, PhD Scientist with operating, company building, fund raising and investment expertise driving growth strategies to develop and commercialize the next generation artificial intelligence-based vaccines, RNA, genetic and precision medicines.R&D – Chief Innovation Officer with 10 FDA approvals, $15B sales, including Adstiladrin®, the first gene therapy approved for bladder cancer and Rebyota®, the first microbiome-based treatment approved for recurring C. difficile infections (100 patents, publications).Venture Creation – launched 4 innovation hubs, set up venture fund and raised $400M in capital. Chaired science and investment committees to identify, incubate and monetize emerging modalities with unmet needs (autoimmune, infectious and rare diseases, immuno-oncology, neuroscience) – 6 exits, 80 deals (buy-sell side, in/ out-licensing) including a $3B M&A with Roivant.Exits – TxCell, Levo Therapeutics, FerGene, Genencor, Centrus and Athenix totaling over $2B.Executive Board – chaired as Chief Biotech Officer. Fellow of the Royal Society (FRS). Executive in Residence – Columbia, Princeton.Board of Directors:* Contera Pharma (2024 – Present)* Caravan Biologix (2024 – Present)* BioEclipse Therapeutics (2022 – Present)* Mid Atlantic Bio Angels (2020 – Present)* Manzara Therapeutics (2017 – 2022)* Academic Venture Exchange (2016 – 2022)* TxCell (2012 – 2018)* Annovis Bio (2012 – 2018)* NanoScan Imaging (2011 – 2017)

Mahmoud Mahmoudian, Phd, Frs's Current Company Details
Summit Impact Partners

Summit Impact Partners

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General Partner, Chief Investment Officer
Cambridge, MA, US
Employees:
3
Mahmoud Mahmoudian, Phd, Frs Work Experience Details
  • Summit Impact Partners
    General Partner, Chief Investment Officer
    Summit Impact Partners
    Cambridge, Ma, Us
  • Summit Impact Partners
    General Partner, Chief Biotech Investment Officer
    Summit Impact Partners 2024 - Present
    Venture Studio – innovators in catalyzing translation of the next generation nature-inspired AI-driven targeted therapies into cures to improve human health.
  • Contera Pharma
    Board Of Directors
    Contera Pharma 2024 - Present
    RNA Therapies – artificial intelligence-based precision medicines for neurological disorders.
  • Caravan Biologix
    Board Of Directors, Chief Corporate Development Officer
    Caravan Biologix 2024 - Present
    Princeton , Nj, Us
    mini-CAR – the first AI-designed mini-CAR therapeutics to revolutionize cancer and hereditary disease treatment.
  • Bioeclipse Therapeutics, Inc
    Board Of Directors, Chief Operating Officer
    Bioeclipse Therapeutics, Inc 2022 - Present
    Mountain View, California, Us
    Immuno-oncology – the next generation AI-generated cancer medicines targeting tumor microenvironment.
  • Mana Therapeutic
    President, Chief Executive Officer
    Mana Therapeutic 2022 - Present
    Immunotherapy – allogeneic cell therapies.
  • Dynamic Cell Therapies, Inc.
    Chief Business Officer
    Dynamic Cell Therapies, Inc. 2022 - Present
    Watertown, Ma, Us
    Cell Therapy – controllable CAR-T cells in solid tumors.
  • Cobro Ventures
    Managing Director
    Cobro Ventures 2022 - 2024
    Mclean, Virginia, Us
    Venture Fund – company building, venture creation and biotech investments operating across its portfolio incubating disruptive scientific breakthroughs.* AI Proteins – Chief Business Officer (mini-proteins)* MANA Therapeutic – President, CEO (cellular medicines)* Dynamic Cell Therapies – Chief Business Officer (tunable CAR-T)
  • Sumitomo Pharma America, Inc.
    Senior Vice President, Head Of Global Oncology External Innovation
    Sumitomo Pharma America, Inc. 2017 - 2022
    Marlborough, Massachusetts, Us
    Headed innovation hubs worldwide – Chief Science Scout leading venture investments and external partnerships with academia, syndicating with venture capital to develop new biology, technologies and treatments in cancer including oRNA – circular RNA ($200M series B).Venture Fund – launched corporate fund as an early-stage investor. Executive Committee – chaired science and investment committees. Worked with board members, scientific advisory board, cross-functional teams (R&D, clinical, regulatory, manufacturing, commercial) to expedite discovery, development and regulatory approvals of novel modalities (RNA therapies, gene editing, artificial intelligence) including Manzara Therapeutics – generative AI.Venture Creation – raised $100M in capital to build academic and venture hubs. Established oncology research alliance with Columbia, Wistar Institute, Harvard and Dana-Farber Cancer Institute. Invested in MPM Capital oncology fund as Limited Partner – member of investor committee. Dana-Farber Innovations Research Fund – $10M investment to discover breakthrough medicines. Roivant – launched Sumitovant in a $3B acquisition (Myovant, Urovant, Enzyvant, Altavant, Spirovant).
  • Ferring Pharmaceuticals
    Vice President, Head Of Innovative Medicines
    Ferring Pharmaceuticals 2012 - 2017
    St-Prex, Ch
    Innovation Hub – global Head reporting to President. Led scientific, commercial due diligence teams to scout, evaluate and develop novel medicines including Rebyota®, the first FDA approved microbiome-based treatment for C. difficile infections.Business Development – raised $100M in capital, formed Trizell SA to commercialize immunotherapy pipeline. Levo Therapeutics – spun off NewCo in rare diseases, raised $40M series A, sold to Acadia Pharma. Ferring Microbiome Institute – joint venture with Intralytix and Karolinska Institute to map human gut microbiota. TxCell – in-licensed OvaSave® (Crohn’s disease), developed and sold to Sangamo for $84M. Launched FerGene – developed Adstiladrin® for bladder cancer with $570M investment from Blackstone.External Research – led investments and incubation of disruptive platforms (mRNA vaccines, phage and gene therapies) for celiac disease, prostate, ovarian and pancreatic cancers including Viventia Bio – antibody drug conjugate, acquired by Eleven Biotherapeutics.
  • Merck
    Managing Director, Business Development & Licensing
    Merck 2007 - 2012
    Merck Bioventures – led scouting, scientific search and evaluation, licensing, venture investments in vaccines and biologics.Business Development – structured deals in immuno-oncology, autoimmune disorders and infectious diseases including acquisition of Sirna – RNA interference to aid drug discovery ($1.1B). GlycoFi – yeast glycosylation platform for antibody production ($400M). Lonza – joint venture for biomanufacture of pneumococcal vaccine (Pneumovax®).External Research – chaired governance committees that included technical transfer, manufacturing and alliance management for GMP scale up and BLA submissions. Led global development teams with multiple FDA approvals and launches – meningococcal vaccine (MenB®), human papillomavirus vaccine (Gardasil®), shingles vaccine (Zostavax®).
  • Dow
    Chief Innovation Officer, Executive Committee
    Dow 2004 - 2007
    Midland, Michigan, Us
    Headed research and development across five sites (US, UK, France, China, Japan) generating $600M sales with 200 reports. Directed global teams that developed products for bio-pharmaceutical applications in emerging markets (China, India, Brazil).Innovation Hub – established biosciences footprint. Identified new technologies for joint ventures, co-development or out-licensing deals with strategic partners. Fresenius – diagnostic kits for sepsis. Sanofi – streamlining insulin production. Genzyme – ophthalmology, biodegradable polymers for targeted delivery. Millipore – development and manufacture of biologics ($100M).Executive Committee – chaired corporate growth at Rohm & Haas (reported to CEO). Member of Emerging Technology Board of Directors. Dow acquired Rohm & Haas in 2007 for $16B.
  • Eastman
    Chief Biotechnology Officer, Board Of Directors
    Eastman 2001 - 2004
    Kingsport, Tennessee, Us
    Recruited by CEO to build biotech hub. Headed global research, implemented strategies for corporate growth and diversification.Innovation Hub – developed broad pipeline, infrastructure that included strategic alliances, targeted divestitures, in/ out-licensing, acquisitions and venture investments. Athenix – $1M investment, sold to Bayer for $400M. Centrus – spun off diagnostics NewCo, sold to Neogene. Altus – acquisition, Enzyme Replacement Therapy for cystic fibrosis. Genencor – metabolic engineering, 51% equity investment, sold to Danisco for $475M.Corporate Development – chaired Biotechnology Board of Directors and investment committee.
  • Glaxosmithkline
    Executive Director, Biopharm R&D
    Glaxosmithkline 1988 - 2001
    Brentford, Middlesex, Gb
    Led global cross-functional drug development teams (discovery, preclinical, clinical, biomanufacturing) in vaccines, biologics and small molecules. FDA approvals – hepatitis B (Lamivudine®), influenza (Relenza®), HIV (Epivir®, Abacavir®, Trizivir®), leukemia (Zygara®), shingles vaccine (Shingrix®), pneumococcal vaccine (Synflorix®).R&D – developed GMP fermentation and biological processes (microbial and mammalian cell cultures, natural products) for multi-ton scale product launches including Relenza® using immobilized recombinant aldolase with 2500 continuous enzyme reuse.External Research – chaired steering committees for key alliances (Amgen, Gilead, Vertex) in neuroscience, anti-infectives, cardiometabolic and inflammatory disorders.

Mahmoud Mahmoudian, Phd, Frs Skills

Business Development Corporate Development Research And Development Alliance Management Portfolio Management Drug Development

Mahmoud Mahmoudian, Phd, Frs Education Details

  • Imperial College London
    Imperial College London
    Doctor Of Philosophy (Phd). Master Of Science (Msc)
  • The Wharton School
    The Wharton School
    Marketing

Frequently Asked Questions about Mahmoud Mahmoudian, Phd, Frs

What company does Mahmoud Mahmoudian, Phd, Frs work for?

Mahmoud Mahmoudian, Phd, Frs works for Summit Impact Partners

What is Mahmoud Mahmoudian, Phd, Frs's role at the current company?

Mahmoud Mahmoudian, Phd, Frs's current role is General Partner, Chief Investment Officer.

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What schools did Mahmoud Mahmoudian, Phd, Frs attend?

Mahmoud Mahmoudian, Phd, Frs attended Imperial College London, The Wharton School.

What skills is Mahmoud Mahmoudian, Phd, Frs known for?

Mahmoud Mahmoudian, Phd, Frs has skills like Business Development, Corporate Development, Research And Development, Alliance Management, Portfolio Management, Drug Development.

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