Malvika Singh Email & Phone Number

Developed a python-based multilayer standalone translational middleware tool to establish interoperability between MedDRA and ICD-10 ontologies and improve clinical trials descriptive reporting workflows

• Supervised day to day operations in the production CAP-accredited and CLIA-certified laboratory responsible for processing 1 million clinical samples/year • Ensured adequate coverage for all assays during the shift by managing call outs and leading daily team huddles for 15+ clinical laboratory scientists and technicians• Operated as shift point of contact on the production floor, monitored performance, and troubleshooted high-throughput automation issues or errors during each phase of an assay in order to quickly identify operational misalignment with SLAs • Conducted biweekly 1:1 meetings with 8 direct reports, wrote performance reviews, and mentored/coached team members • Developed the validation and launch of RPGR (ORF15) gene for X-linked retinitis pigmentosa test to support the diagnostic and predictive panel • Coordinated new assay validation and development for release (including quant/norm/sort/stamp integration, RPGR sequencing, alternative labware contingency testing, FDA validation testing, LIMS UI design and upgrade, etc)• Proposed and implemented workflow pivots for mainline NGS, NIPS and 7 confirmatory assays to accommodate challenges by determining how equipment/instrumentation capacity and timing impacted TAT• Identified and escalated operational incidents via change management, incident reporting and jira ticketing • Monitored team safety and ensured adherence to EH&S and regulatory requirements• Served on the interview panel and hosted 20+ interviews for the selection of clinical laboratory scientists and technicians

San Francisco Bay Area

• Maintained proficiency in mainline Next Generation Sequencing, Non-Invasive Prenatal Screening (NIPS), Sanger Sequencing, Polymerase Chain Reaction (PCR), Multi-Ligation Probe Amplification (MLPAseq), FMR1 RP-PCR, C9orf72, Microarray-based Comparative Genomic Hybridization, PacBio SMRT cell sequencing, NovaSeq and HiSeq use and maintenance• Developed and maintained laboratory SOPs• Maintained proficiency in Agilent Bravo, Hamilton STARlet, Dynamic Devices Lynx, Hamilton Verso automated storage system, ThermoFisher Qubit, Covaris Ultrasonicator, Trinean DropSense, ABI 3500XL Genetic Analyzer and ThermoFisher Nanodrop use

Master Of Science - Ms, Biomedical Informatics, Concentration In Bioinformatics, 4.0/4.0

Relevant Coursework: Concepts in Computer Programming, Advanced Bioinformatics: Genome Analysis, Machine Learning for Biomedical.

Bachelor Of Science - Bs, Biochemistry, Minor In Chemistry