Marc Singleton Email and Phone Number
I am a computational biologist with experience in deriving meaningful insights from high-dimensional data seeking to apply state-of-the-art methods to diverse biological questions. My strong foundation in traditional statistical modeling and modern machine learning techniques complements a deep expertise in modeling biological sequences, and I excel at translating technical concepts to diverse audiences.You can view my work here:https://github.com/marcsingletonBackground photo:A network representation of homology relationships where nodes represent protein sequences in 33 different Drosophila genomes and edges represent best reciprocal hits between those sequences resulting from BLAST searches. Orthologous groups of proteins can be defined as sets of densely connected nodes.
Sandia National Laboratories
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Postdoctoral AppointeeSandia National Laboratories Jul 2024 - PresentLivermore, California, United States -
Postdoctoral AssociateHoward Hughes Medical Institute May 2023 - May 2024Berkeley, California, United States• Trained generative deep learning models based on transformer and diffusion architectures to learn meaningful representations of disordered proteins -
Graduate Student Researcher (Biophysics Graduate Program)University Of California, Berkeley Aug 2017 - May 2023• Designed a bioinformatics pipeline in Python to robustly identify and align orthologous proteins in 33 Drosophila genomes using BLAST searches conducted on HPC clusters and graph clustering techniques• Conducted multivariate analyses of over 40 biochemical features associated with disordered regions in the aligned proteins using statistical models of trait evolution• Implemented algorithms for fitting mixture models and HMMs to data and published the code as two standalone packages to PyPI alongside tutorials illustrating their use -
Postbaccalaureate FellowNational Center For Advancing Translational Sciences (Ncats) May 2016 - Jul 2017Rockville, Maryland, United States• Optimized UPLC-MS/MS methods for the analysis of animal pharmacokinetic studies of candidate drug compounds for several concurrent projects with diverse stakeholders, contributing to three publications
Marc Singleton Education Details
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Biophysics -
Chemistry, Mathematics
Frequently Asked Questions about Marc Singleton
What company does Marc Singleton work for?
Marc Singleton works for Sandia National Laboratories
What is Marc Singleton's role at the current company?
Marc Singleton's current role is Computational Biologist.
What schools did Marc Singleton attend?
Marc Singleton attended University Of California, Berkeley, Vanderbilt University.
Who are Marc Singleton's colleagues?
Marc Singleton's colleagues are Yvonne Pacheco, Doug Hanson, Pam Catanach, Steven Rouse, Brendon Mizener, Kathleen Galbraith, Keith Morris.
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Marc Singleton
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Marc Singleton, MS, MA
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