Marc Singleton

Marc Singleton Email and Phone Number

Computational Biologist @ Sandia National Laboratories
albuquerque, new mexico, united states
Marc Singleton's Location
Oakland, California, United States, United States
About Marc Singleton

I am a computational biologist with experience in deriving meaningful insights from high-dimensional data seeking to apply state-of-the-art methods to diverse biological questions. My strong foundation in traditional statistical modeling and modern machine learning techniques complements a deep expertise in modeling biological sequences, and I excel at translating technical concepts to diverse audiences.You can view my work here:https://github.com/marcsingletonBackground photo:A network representation of homology relationships where nodes represent protein sequences in 33 different Drosophila genomes and edges represent best reciprocal hits between those sequences resulting from BLAST searches. Orthologous groups of proteins can be defined as sets of densely connected nodes.

Marc Singleton's Current Company Details
Sandia National Laboratories

Sandia National Laboratories

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Computational Biologist
albuquerque, new mexico, united states
Website:
sandia.gov
Employees:
8667
Marc Singleton Work Experience Details
  • Sandia National Laboratories
    Postdoctoral Appointee
    Sandia National Laboratories Jul 2024 - Present
    Livermore, California, United States
  • Howard Hughes Medical Institute
    Postdoctoral Associate
    Howard Hughes Medical Institute May 2023 - May 2024
    Berkeley, California, United States
    • Trained generative deep learning models based on transformer and diffusion architectures to learn meaningful representations of disordered proteins
  • University Of California, Berkeley
    Graduate Student Researcher (Biophysics Graduate Program)
    University Of California, Berkeley Aug 2017 - May 2023
    • Designed a bioinformatics pipeline in Python to robustly identify and align orthologous proteins in 33 Drosophila genomes using BLAST searches conducted on HPC clusters and graph clustering techniques• Conducted multivariate analyses of over 40 biochemical features associated with disordered regions in the aligned proteins using statistical models of trait evolution• Implemented algorithms for fitting mixture models and HMMs to data and published the code as two standalone packages to PyPI alongside tutorials illustrating their use
  • National Center For Advancing Translational Sciences (Ncats)
    Postbaccalaureate Fellow
    National Center For Advancing Translational Sciences (Ncats) May 2016 - Jul 2017
    Rockville, Maryland, United States
    • Optimized UPLC-MS/MS methods for the analysis of animal pharmacokinetic studies of candidate drug compounds for several concurrent projects with diverse stakeholders, contributing to three publications

Marc Singleton Education Details

Frequently Asked Questions about Marc Singleton

What company does Marc Singleton work for?

Marc Singleton works for Sandia National Laboratories

What is Marc Singleton's role at the current company?

Marc Singleton's current role is Computational Biologist.

What schools did Marc Singleton attend?

Marc Singleton attended University Of California, Berkeley, Vanderbilt University.

Who are Marc Singleton's colleagues?

Marc Singleton's colleagues are Yvonne Pacheco, Doug Hanson, Pam Catanach, Steven Rouse, Brendon Mizener, Kathleen Galbraith, Keith Morris.

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