Marc Singleton
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Marc Singleton Email & Phone Number

Computational Biologist at Sandia National Laboratories
Location: Oakland, California, United States 4 work roles 2 schools
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Role
Computational Biologist
Location
Oakland, California, United States
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Who is Marc Singleton? Overview

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Marc Singleton is listed as Computational Biologist at Sandia National Laboratories, a company with 8667 employees, based in Oakland, California, United States. AeroLeads shows a matched LinkedIn profile for Marc Singleton.

Marc Singleton previously worked as Postdoctoral Appointee at Sandia National Laboratories and Postdoctoral Associate at Howard Hughes Medical Institute. Marc Singleton holds Doctor Of Philosophy - Phd, Biophysics from University Of California, Berkeley.

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Sandia National Laboratories

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Profile bio

About Marc Singleton

I am a computational biologist with experience in deriving meaningful insights from high-dimensional data seeking to apply state-of-the-art methods to diverse biological questions. My strong foundation in traditional statistical modeling and modern machine learning techniques complements a deep expertise in modeling biological sequences, and I excel at translating technical concepts to diverse audiences.You can view my work here:https://github.com/marcsingletonBackground photo:A network representation of homology relationships where nodes represent protein sequences in 33 different Drosophila genomes and edges represent best reciprocal hits between those sequences resulting from BLAST searches. Orthologous groups of proteins can be defined as sets of densely connected nodes.

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Sandia National Laboratories
Sandia National Laboratories
Computational Biologist
albuquerque, new mexico, united states
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Employees
8667
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4 roles

Marc Singleton work experience

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Postdoctoral Associate

Berkeley, California, United States

  • Trained generative deep learning models based on transformer and diffusion architectures to learn meaningful representations of disordered proteins
May 2023 - May 2024

Graduate Student Researcher (Biophysics Graduate Program)

  • Designed a bioinformatics pipeline in Python to robustly identify and align orthologous proteins in 33 Drosophila genomes using BLAST searches conducted on HPC clusters and graph clustering techniques
  • Conducted multivariate analyses of over 40 biochemical features associated with disordered regions in the aligned proteins using statistical models of trait evolution
  • Implemented algorithms for fitting mixture models and HMMs to data and published the code as two standalone packages to PyPI alongside tutorials illustrating their use
Aug 2017 - May 2023

Postbaccalaureate Fellow

Rockville, Maryland, United States

  • Optimized UPLC-MS/MS methods for the analysis of animal pharmacokinetic studies of candidate drug compounds for several concurrent projects with diverse stakeholders, contributing to three publications
May 2016 - Jul 2017
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Colleagues at Sandia National Laboratories

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2 education records

Marc Singleton education

Doctor Of Philosophy - Phd, Biophysics

Dissertation: Finding structure in disorder: Evolutionary analyses of disordered proteins in Drosophila

Bachelor Of Arts - Ba, Chemistry, Mathematics

Graduated summa cum laude and Phi Beta Kappa membership

FAQ

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What company does Marc Singleton work for?

Marc Singleton works for Sandia National Laboratories.

What is Marc Singleton's role at Sandia National Laboratories?

Marc Singleton is listed as Computational Biologist at Sandia National Laboratories.

Where is Marc Singleton based?

Marc Singleton is based in Oakland, California, United States while working with Sandia National Laboratories.

What companies has Marc Singleton worked for?

Marc Singleton has worked for Sandia National Laboratories, Howard Hughes Medical Institute, University Of California, Berkeley, and National Center For Advancing Translational Sciences (Ncats).

Who are Marc Singleton's colleagues at Sandia National Laboratories?

Marc Singleton's colleagues at Sandia National Laboratories include Stacey Long Reynolds, Miriam Maldonado, Jon Wegener, Amy Varner, Mba, Pmp, and Ana Baca.

How can I contact Marc Singleton?

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What schools did Marc Singleton attend?

Marc Singleton holds Doctor Of Philosophy - Phd, Biophysics from University Of California, Berkeley.

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