Marc Unger Email & Phone Number

California, United States

• Founded Hyalos with Professor Paul Bollyky and Nadine Nagy of Stanford University, based on first-in-class oral drugs which induce regulatory T cells by inhibition of hyaluronic acid. Treg induction has promise against.
• Formed the company, raised seed funding, recruited CFO, CMO, and medicinal chemist; developed company strategy; negotiated IP license with Stanford; filed IND with US FDA; organized clinical trial; shut the company.

South San Francisco, California, US

• Member of the Executive Staff: set company strategy and goals, performed diligence for potential deals and acquisitions, and presented to the Board of Directors. Drove R&D Portfolio Management and New Product.
• Stabilized, restructured, built out, and managed the Marketing organization: reorganized the department around business objectives, supported sales organization, product management, and strategic marketing.
• Managed both Marketing and genomics R&D. Recruited high-caliber, experienced senior VPs for Marketing and R&D.

South San Francisco, California, US

• Member of the Executive Staff: duties as above.
• Responsible for all genomics product development at Fluidigm – Single-Cell and Production Genomics product lines; instrumentation, microfluidic chips, reagents, and software.
• Responsible for all genomic research and technology development at Fluidigm – new hardware platforms, microfluidic research, molecular biology protocol development, single cell biology applications, and bioinformatics..
• Manage the genomics R&D organization: recruit and organize the team, manage the project portfolio and budget (> $20M/year), track goals and objectives, report progress.

South San Francisco, California, US

• Championed, and responsible for development of, Fluidigm’s Single-Cell Genomics product line – C1 instrument, microfluidic chips, protocols, and bioinformatic package for single cell genomic analysis. The C1 was a.
• Extended high-throughput PCR product lines: new chip formats (96.96, 192.24, and FlexArray), new chemistries (DeltaGene reagents for gene expression, SNP Type reagents for genotyping), and assay design services.
• Led development of a system for cell biology (the Stem Cell Culture System, with a grant from the California Institute of Regenerative Medicine).
• Drove new technology development: created the Gen 2 platform, increasing the control complexity of microfluidic chips by six orders of magnitude; built fluidic logic, enabling autonomous chip control; integrated.
• Managed steadily increasing amounts of the R&D organization, budget, project portfolio, and product development process.

South San Francisco, California, US

• Led development of and launched the BioMark product line: instrumentation, reagents, software, and microfluidic chips for Gene Expression, Genotyping, and Digital PCR. BioMark gives orders-of-magnitude advantages over.
• Invented and developed the integrated carrier, Fluidigm’s now-standard commercial “world to chip” interface. Carrier was developed for Fluidigm’s first product line and subsequently implemented for all product lines.
• Extended fabrication process capabilities, increased throughput, and dramatically reduced chip cost through continued development of fabrication tools and technology.

South San Francisco, California, US

• Invented and implemented fundamental MSL fabrication tools and technology.
• Drove new device design and characterization (e.g. normally closed valves, multiplexers)
• Led team to establish feasibility of high-throughput PCR in chip.
• Taught “Microfluidics 101” (and 102) to train Fluidigm employees in the basics of microfluidics (and microfluidic engineering)
• Helped establish Fluidigm’s fundamental IP position

Pasadena, CA, US

• Invented Multilayer Soft Lithography. MSL enables the creation of active valves and pumps using silicone rubber (PDMS). Science paper has > 2500 citations.
• Built surface chemistry for attaching DNA to surfaces with retention of full ability to serve as enzyme (e.g. polymerase) substrate. Chemistry adopted and used by Helicos (single molecule sequencing company).
• Imaged single fluorophore molecules with a conventional fluorescence microscope.

Stanford Executive Institute - August 5-15, 2012

Phd, Chemistry

B.S., Chemistry