Mariana Bego
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Mariana Bego Email & Phone Number

Manager AAV Plasmid Production & Process Development @ Alexion | Senior Principal Scientist at Alexion Pharmaceuticals, Inc.
Location: Carrboro, North Carolina, United States 17 work roles 3 schools
1 work email found @ircm.qc.ca LinkedIn matched
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Role
Manager AAV Plasmid Production & Process Development @ Alexion | Senior Principal Scientist
Location
Carrboro, North Carolina, United States
Company size

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Mariana Bego is listed as Manager AAV Plasmid Production & Process Development @ Alexion | Senior Principal Scientist at Alexion Pharmaceuticals, Inc., a company with 1001 employees, based in Carrboro, North Carolina, United States. AeroLeads shows a work email signal at ircm.qc.ca and a matched LinkedIn profile for Mariana Bego.

Mariana Bego previously worked as Senior Principal Scientist- - Manager AAV Process Development & Plasmid Production. at Alexion Pharmaceuticals, Inc. and Principal Scientist- Manager AAV Process Development & Plasmid Production. at Alexion Pharmaceuticals, Inc.. Mariana Bego holds Phd, Molecular And Cell Biology from University Of Nevada, Reno.

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Profile bio

About Mariana Bego

As a Manager of AAV Process Development and Plasmid Production and a Principal Scientist at Alexion, Astra Zeneca Rare Disease, I oversee the plasmid production group and lead the development of new methods and processes to facilitate innovations in AAV manufacturing. With 20 years of experience in research and development, I have a strong background in cell biology, innate immunity, biochemistry, and human retrovirology, as well as a proven track record of designing, optimizing, and interpreting experimental outcomes and leading research teams.My mission is to solve scientific problems and contribute to the advancement of human health, using my curious and creative mindset and my passion for learning and discovery.

Listed skills include Virology, Molecular Biology, Immunology, Dna, and 36 others.

Current workplace

Mariana Bego's current company

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Alexion Pharmaceuticals, Inc.
Alexion Pharmaceuticals, Inc.
Manager AAV Plasmid Production & Process Development @ Alexion | Senior Principal Scientist
121 Seaport Blvd, Boston, MA 02210, USA
Website
Employees
1001
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17 roles

Mariana Bego work experience

A career timeline built from the work history available for this profile.

Senior Principal Scientist- - Manager Aav Process Development & Plasmid Production.

Current

Boston, Massachusetts, US

Jun 2024 - Present

Principal Scientist- Manager Aav Process Development & Plasmid Production.

Boston, Massachusetts, US

Sep 2023 - May 2024

Manager Aav Process Development & Plasmid Production. Principal Scientist

New York, New York, US

  • Oversee the plasmid production group: Manage production schedule, material sourcing & inventory, adhere to tight timelines & deliverables, coordinate with various other units to meet requests and advise project leads.
  • Actively seek to adapt methods to improve capacity and optimize the plasmid production process.
  • Lead the development of new methods/processes to facilitate innovations in AAV manufacturing.
  • Take the initiative to solve scientific problems and contribute to their resolution. Able to work in a fast-paced team environment with changing priorities.
  • Contribute to the design and optimization of AAV constructs and capsids
  • Act as team lead for cross unit support in gene therapy portfolio development
Oct 2021 - Sep 2023

Guest Associate Editor

Lausanne, Vaud, CH

Editorial responsibilities: assessing manuscripts fit within the scope of the special issue, overseeing peer-review process and making a final suitability for publication decision. Research topic of collection: "Immune determinants of COVID-19 protection and disease: a Focus on Asymptomatic COVID and Long COVID"Deadline for abstract submissions: 27 July.

May 2021 - Sep 2022

Founder And Director

- Fresh and new business model, 100% women owned and led; and targeting towards building a 70% women and minority team of experts across the world to bring you top-notch certified DNA testing services and advice in your own language, whatever that would be!-On first quarter focused on building our team, securing accreditation, launching our marketing.

Apr 2021 - Apr 2022

Research Associate

Montreal, Quebec, CA

The Government of Canada launched the COVID-19 Immunity Task Force (CITF) to track the spread of the virus in both the general population and priority populations in Canada. The Task Force also aims to shed light on immune responses to SARS-CoV-2 in a diversity of communities, age brackets, populations, and occupational groups across the nation. To.

Nov 2020 - Oct 2021

Research Associate At School Of Population And Global Health

Montreal, Qc, CA

Nov 2020 - Oct 2021

Business Partner / Advisor

Sparks, NV, US

- Redefined company short- and long-term goals. Led restructure of operations, design and implementation of new business model that lowers fixed and overhead cost to maximize initial investment returns and projected profits. - Created new business plan; updating marketing plans, market studies and regulatory requirements. Generated support material to back.

Oct 2020 - Apr 2021

Research Associate

Montréal, Québec, CA

- Discovered novel innate immunity evasion mechanism exploited by worldwide epidemic HIV-1 strains absent in African-restrained viruses. This work yielded four first author publications and secured external funding.- Assessed toxicity and antiviral potency of FDA-approved anticancer drugs to identify novel targets for anti-retroviral intervention.- Exposed.

Jan 2011 - Oct 2020

Postdoctoral Fellow

Montréal, Québec, CA

- Studied modulation of HIV-1-host interaction and the role of the HIV-1 accessory protein Vpu. - Elucidated immune regulation of BST2/Tetherin gene. BST2 protein has two very important roles, it is a key effector of the innate immune system and it is also responsible for preventing release of newly form virus particles from the infected cell. It is know.

Jun 2008 - Dec 2010

Assistant Professor

Reno, NV, US

- Main Instructor Molecular Biology Laboratory (BCH406/606). Department of Biochemistry.- Organizer of class Molecular Mechanism of viral replication (MICR 784). Microbiology graduate program).- Invited lecturer: Molecular Cell Biology (CMB 710- Cell and Molecular Biology graduate program) and Principles in Genetics (BIOL 300-undergraduate Biology program).

Jan 2006 - Jun 2008

Postdoctoral Fellow

Reno, NV, US

- Discovered the first-described Human Cytomegalovirus latency protein and developed one ELISA-based assay to detect its presence in naturally infected human samples. - Coordinated a multi-disciplinary collaboration and trained multiple students.- My graduate and post-graduate work yielded seven publications (3 first authored and 4 co-author.

Jan 2006 - Jun 2008

Consultant

Sparks, NV, US

- Developed and maintained all Standard Operating Procedures (SOPs) and Quality Assurance/ Quality Control (QA/QC) documents, required for federal accreditation and ISO certification of forensic DNA assays.

Jan 2006 - Jun 2008

Teaching Assistant

Reno, NV, US

- Teaching Assistance for Department of Biochemistry, Molecular Biology Laboratory (BCH406/606).

Jan 2005 - Jul 2005

Research Associate

Reno, NV, US

- Fellowship at University of Nevada. Research project: “Development of Recombinant Hantavirus Antigens for Serologic Diagnosis with Homologous Serotype.”- Developed an IgM ELISA assay to detect the presence of anti-hantavirus IgM specific antibodies in their Natural Host, and study of virus circulation in wild rodent populations.- Developed an IgG ELISA.

Sep 2001 - Jun 2003

Research Fellow

National Research Institute Of Human Viral Diseases, Dr Julio Maiztegui

- Studied the dynamics of Biosafety level 4 Hantavirus infection in rodents and human populations. - Awarded with Scientific Exchange Fellowship from International Society for Infectious Disease.

Jan 1999 - Sep 2001
Team & coworkers

Colleagues at Alexion Pharmaceuticals, Inc.

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3 education records

Mariana Bego education

Phd, Molecular And Cell Biology

University Of Nevada, Reno

Ms In Pharmacy, Forensics Dna And Serology

University Of Florida

Licenciatura (Bs/Ms Equivalent), Biotechnology

Universidad Nacional De Rosario
FAQ

Frequently asked questions about Mariana Bego

Quick answers generated from the profile data available on this page.

What company does Mariana Bego work for?

Mariana Bego works for Alexion Pharmaceuticals, Inc..

What is Mariana Bego's role at Alexion Pharmaceuticals, Inc.?

Mariana Bego is listed as Manager AAV Plasmid Production & Process Development @ Alexion | Senior Principal Scientist at Alexion Pharmaceuticals, Inc..

What is Mariana Bego's email address?

AeroLeads has found 1 work email signal at @ircm.qc.ca for Mariana Bego at Alexion Pharmaceuticals, Inc..

Where is Mariana Bego based?

Mariana Bego is based in Carrboro, North Carolina, United States while working with Alexion Pharmaceuticals, Inc..

What companies has Mariana Bego worked for?

Mariana Bego has worked for Alexion Pharmaceuticals, Inc., Pfizer, Frontiers, Genquest Dna, and Covid-19 Immunity Task Force | Groupe De Travail Sur L’Immunité Face À La Covid-19.

Who are Mariana Bego's colleagues at Alexion Pharmaceuticals, Inc.?

Mariana Bego's colleagues at Alexion Pharmaceuticals, Inc. include Omnath Gupta, Leigh Funston, Michael Gapinske, Linghe Xi, and Martin Müller.

How can I contact Mariana Bego?

You can use AeroLeads to view verified contact signals for Mariana Bego at Alexion Pharmaceuticals, Inc., including work email, phone, and LinkedIn data when available.

What schools did Mariana Bego attend?

Mariana Bego holds Phd, Molecular And Cell Biology from University Of Nevada, Reno.

What skills is Mariana Bego known for?

Mariana Bego is listed with skills including Virology, Molecular Biology, Immunology, Dna, Biochemistry, Cell Biology, Microbiology, and Biotechnology.

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