Mark Gregory Email & Phone Number

United States

• Development and maintenance of Spatial biology analysis pipelines and infrastructure for CosMx early Technology Access Program at commercial scale (100s of projects, 1000s of samples).• Designed the data structure export structure and visualizations for leading spatial biology platfrom, CosMx SMI.• Method development for emerging spatial biology platforms, ex. Spatially informed Differential Expression methods and cell type annotation tools.• Lead collaborations with external KOLs in the spatial biology field, coordinating cross-functional teams to generate and present novel findings at scientific conferences.

Greater Seattle Area

• Lead Core Chemistry team developing solutions for the hybridization-based NGS sequencing platform Hyb & Seq.• Develop and maintain pipelines for large NGS data analysis and interpretation.• Develop library preparation methods for multiple NGS platforms.• Lead external collaborations with key collaborators and present at national conferences.• Manage small team of research associates.

Greater Seattle Area

• Developed a novel NGS technology (CypherSeq) for rare-variant detection applications.• Developed custom DNA sequencing analysis pipelines and visualization tools for CypherSeq-based projects.• Algorithm optimization to expand throughput including runtime reduction, parallel processing, and cluster utilization.• Investigated mechanisms and chemistries for high-accuracy, targeted DNA sequencing.• Applied DNA sequencing-based approaches to non-invasive ovarian cancer screening using genetic biomarkers.

Bethesda, Md

Lead research projects investigating the structures and mechanisms of DNA Polymerase Eta, the Artemis nuclease, and kinesin motor proteins. Characterized a novel platinum-based chemotherapeutic agent, phenanthriplatin, and its effects on DNA replication using biochemical and crystallographic techniques.

Doctor Of Philosophy (Ph.D.), Cell, Molecular, Developmental Biology, And Biophysics

Master'S Degree, Biochemistry And Molecular Biophysics

Bachelor'S Degree, Biochemistry And Molecular Biophysics