Mark Vitucci Email & Phone Number

United States

Durham, NC

Oversee the Array Services team responsible for expression and genotyping microarrays, qPCR on the Fluidigm platform, and Nanostring. Role involves managing tens of projects at once in a regulated environment to ensure timelines and revenue targets are met. I train and mentor a staff of 7, assess quality control of data, collaborate with bioinformatics and.

RTP

Led independent project to develop and validate competitive internal sequencing standards on the Ion Torrent PGMDesign amplicon sequencing for single-copy phylogenetic markers for quantifying microorganisms present in human lower respiratory infections.Ion Torrent PGM operation and sequencing analysis

Project manager for a contracted study to perform RNA-seq on recurrent GBM and validate a predictive 43-gene signature. Coordinated with multiple cores to coordinate sample processing and sequencing under deadlines, reported periodic results, managed billing, sequencing analysis.RNA-seq analysis for 2 The Cancer Genome Atlas Lower-grade Glioma Project.

Implemented microarray procedures and analysis. Applied custom R scripts to examine transcriptome profiles in humans and mice.Molecular characterization of cell lines and genetically-engineered mouse models of astrocytoma using bioinformatic analyses of gene expression and copy number data. Multiple dataset combination and cross-species analyses between.

Used genetically-engineered mice to 1) Investigate the effects of endogenous and exogenous IL-4 on CD8+ T cell regulation.2) Quantification of the differential modulation of IgD and IgM after exposure to self-antigen.

Investigate mechanisms of chronic obstructive pulmonary disease by exposing mice to airway irritants.

Doctor Of Philosophy (Phd), Genetics And Molecular Biology/Cancer Biology

Bs, Microbiology And Molecular Genetics