Matthew Walker work email
- Valid
- Valid
- Valid
Matthew Walker personal email
Translational Scientist with over fifteen years’ experience in assay development, drug development, identification of new therapeutic targets, and signal transduction with subject matter expertise in orphan diseases, respiratory diseases, ocular diseases, immunology, and cancer biology. Open minded and creative scientist with experience in working with cross-functional teams. Excellent communication skills evidenced by multiple funded research grants, successful patent applications, numerous presentation awards and invited lectures, and a strong publication record.
-
Head Of Element GenomicsUcbChapel Hill, Nc, Us -
Head Of Element Genomics BiologyUcb Mar 2024 - Present
-
Senior Principal ScientistUcb Apr 2020 - Jul 2024Ucb ElementBiology Project Lead at UCB Element, the functional genomics arm of UCB. Leads team to perform functional genomics screens and complex cellular models for UCB portfolio projects and for new target identification.
-
Senior ScientistElement Genomics Jul 2019 - Apr 2020
-
Biology LeadVitrisa Therapeutics Nov 2017 - Apr 2019Raleigh-Durham, North Carolina Area• Lead biologist in cross functional project team that managed timelines and presented to senior leadership.• Created screening cascade to support hit to lead characterization within the Target Product Profile.• Oversaw screening of over 300 compounds leading to 2 nominated IND candidates• Contributing author on 3 patent applications by generating and summarizing data for examples, white paper drafting, and participating in review discussion with patent counsel. • Developed precision medicine approach to identify patients that matched the mechanism of action.• Developed expertise in GPCR signaling, ocular diseases, cell models of ocular disease, and immunology. -
Principal ScientistSpyryx Biosciences Jun 2016 - Nov 2017• Developed and wrote 4 Standard Operating Procedures, worked with four CROs, and contributed to 5 research reports on molecular mechanisms of lead compound • Contributed data for 2 patent applications, aided in writing investigational brochure and IND documents, and one funded SBIR • Second author on paper describing the pre-clinical research • Organized and led team to publish pre-clinical toxicology • Presented data and represented the Spyryx scientific team at 3 national meetings and 1 invited lecture • Developed expertise in ion channel biology, cystic fibrosis and cell and animal models of lung diseases -
Postdoctoral FellowUniversity Of North Carolina At Chapel Hill Oct 2010 - May 2016Chapel HillDevelopment of functional genomic screening platforms.- Adapted the haploid mutagenesis screening approach to perform genome wide loss-of-function screens on transcriptional reporters. - Construction of a lentiviral kinase library to enable gain of function kinome screening. - Developed CDt/MS, a novel gain-of-function screening platform. - CRISPR genome wide loss of function screening.Identified FOXP1 as an activator of Wnt signaling in Diffuse Large B-Cell Lymphoma. - Determined the mechanism by which FOXP1 activates Wnt signaling. - Led efforts to define the role of FOXP1 and Wnt signaling in diffuse large B-cell lymphomas through mouse models and human tumor samples. - Kinase activity profiling on DLBCL cell lines.Identified AAK1 as a negative regulator of Wnt signaling - Determined that AAK1 regulates clatharin mediated endocytosis of LRP6- Led efforts to define the global impact of AAK1 on membrane proteins and kinase activity using shotgun mass-spectrometry -
Graduate StudentUniversity Of Chicago Sep 2004 - Oct 2010Used phage display to identify Estrogen Receptor Alpha (ERα) interacting proteins.- Characterized RAC3, a rho family, small GTP binding protein, as a novel coactivator of ERα that promotes migration.Set up a drug discovery facility with automated, high content screening capabilities.- Assisted other laboratories with the design and implementation of chemical screens and instruction on how to use the equipment.- Developed a chemical screen to identify compounds that alter the localization of ERα and other steroid receptors.
Matthew Walker Skills
Matthew Walker Education Details
-
Cancer Biology
-
Biochemistry
Frequently Asked Questions about Matthew Walker
What company does Matthew Walker work for?
Matthew Walker works for Ucb
What is Matthew Walker's role at the current company?
Matthew Walker's current role is Head of Element Genomics.
What is Matthew Walker's email address?
Matthew Walker's email address is ma****@****ago.edu
What schools did Matthew Walker attend?
Matthew Walker attended The University Of Chicago, Florida State University.
What are some of Matthew Walker's interests?
Matthew Walker has interest in New Technology, Trail Running, Cooking, Cycling, Cancer Biology.
What skills is Matthew Walker known for?
Matthew Walker has skills like Molecular Biology, Molecular Cloning, Western Blotting, Pcr, Fluorescence Microscopy, Teaching, Research, Confocal Microscopy, Cell Culture, Protein Chemistry, Biochemistry, Genomics.
Who are Matthew Walker's colleagues?
Matthew Walker's colleagues are Kumar Pcb, Adriano Ribeiro, Peter Robinson, Romario Mizaha, Syed Hasan, Jianxiao Zou, Olya Antonenko.
Not the Matthew Walker you were looking for?
-
Matthew Walker
Greater Montgomery Area4gmail.com, perspecta.com, gmail.com, peoplepc.com -
Matthew Walker
West Hartford, Ct -
5gmail.com, coloradogolf.org, comedyworks.com, denverathleticclub.org, coloradogolf.org -
Matthew Walker
Atlanta, Ga -
Free Chrome Extension
Find emails, phones & company data instantly
Download 750 million emails and 100 million phone numbers
Access emails and phone numbers of over 750 million business users. Instantly download verified profiles using 20+ filters, including location, job title, company, function, and industry.
Start your free trial