Mathieu Chellat Email & Phone Number

Bern Area, Switzerland

Bern, Berne, Switzerland

Basel Area, Switzerland

My responsibilities include:- Planning and tracking of all regulatory events and milestones in a GMP environment.- Maintaining the regulatory submission planning and registration tracking databases (RIMS).- Supporting Global Regulatory Affairs.- Close communication and cooperation with other GRA functions across the globe.- Trackwise, SharePoint, Documentum, PlateauContact:Email: mathieu.chellat@agap2.ch

Lausanne Area, Switzerland

Establish a general methodology to evaluate biomolecular targets of metal complexes with antitumor properties and obtain detailed interaction information at a molecular level.

Wädenswil, Switzerland

• Interdisciplinary collaboration project with BioVersys AG, Basel on antibiotic resistance, supported by the Swiss Commission for Technology and Innovation (CTI)• Synthesized over 300 Transcription Repressor Inhibitory Compounds (drug-like small molecules) via multistep chemical synthesis.• Established structure activity relationships for 2 different targets.• Used biological data and modeling studies for the design of new compounds.• Ran PK analytics of in vivo studies on… Show more • Interdisciplinary collaboration project with BioVersys AG, Basel on antibiotic resistance, supported by the Swiss Commission for Technology and Innovation (CTI)• Synthesized over 300 Transcription Repressor Inhibitory Compounds (drug-like small molecules) via multistep chemical synthesis.• Established structure activity relationships for 2 different targets.• Used biological data and modeling studies for the design of new compounds.• Ran PK analytics of in vivo studies on triple-quad UPLC-MS.• Documentation of project-relevant data within the internal electronic data management system.• Close interaction with biologists with respect to in vitro and in vivo experiments. Show less

Geneva, Switzerland

• Developed and optimized new organocatalysis reactions.• Investigated point-to-planar chirality transfer reactions.• Synthesized novel heterocyclic scaffolds using organocatalysis.• Synthesized 1,4-diketones via domino asymmetric conjugate additions.

Columbus, Oh

• Completed the synthesis of the core of marine macrolide leiodelide A in 17 steps.• Studied the mechanism and improved the yield of the iodooxazole halogen dance reaction from 35% to 81%.• Discovered a one-step procedure for the reduction and deprotection of homoallylic benzyl ethers.

Durham, Nc

• Synthesis of the core of hepatitis C protease inhibitor boceprevir.• Collaboration with Merck on the synthesis of novel antifungal agents derived from the triterpeneglycoside enfumafungin.

Phd, Chemistry

M.S., Chemistry