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Min Wang Email & Phone Number

Senior Scientist at Amgen
Location: South San Francisco, California, United States 7 work roles 3 schools
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Current company
Amgen
Role
Senior Scientist
Location
South San Francisco, California, United States

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Min Wang is listed as Senior Scientist at Amgen, based in South San Francisco, California, United States. AeroLeads shows a matched LinkedIn profile for Min Wang.

Min Wang previously worked as Research Engineer at Stanford University and Postdoctoral Scholar at Stanford University. Min Wang holds Postdoctoral Fellow, Human Gut Microbiome from Stanford University.

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About Min Wang

Highly motivated and self-driven chemist with a strong background in drug metabolism, human gut microbiome, and natural product biosynthesis. Easy-going person who enjoyed working in a collaborative manner and/or in a multi-disciplinary team. Passionate about translating science and bringing technical innovations into therapeutics for human disease.During my PhD, I focused on the biosynthetic mechanism that bacteria use to produce the lincosamide antibiotics, Lincomycin A and celesticetin. In my first project, I was obsessed with the mysterious origin of sulfur atom in the structure of lincomycin A, which has been used in clinic for more than half a century. As part of teamwork, I discovered an unprecedented role of two small-molecule thiols, ergothioneine and mycothiol, which act as assembly template and sulfur donor, respectively. In my second project, I followed up to solve the enzymatic mechanism that drive the distinct S-functionalization of lincosamide antibiotics. These works had resulted in the publications in top journals, including Nature and JACS. Fascinated by the microbial metabolism, I continued my postdoc training in a new field, human gut microbiota, by which hundreds of small molecules are produced to impact human health and disease. To establish causality and mechanism of interactions between microbiome and host, I developed a novel framework to interrogate the biological function of single niche/strain/molecule in a highly complex microbiome model.Throughout my academic training, I cultivated all the techniques, strategic thinking, and problem-solving skills, that are critical to be a successful scientist. In addition, I also developed some important attributes that I believe will have a longer impact on my career development, including but not limited to, fast learning/teamwork and collaboration/project management/detail orientation/diligency and efficiency

Listed skills include Microbiome, Metabolomics, Microbiota, In Vivo, and 26 others.

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Amgen
Amgen
Senior Scientist
Website
amgen.com
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7 roles

Min Wang work experience

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Senior Scientist

Current
Amgen

Thousand Oaks, Ca, Us

Jan 2023 - Present

Postdoctoral Scholar

Stanford University

Stanford, Ca, Us

-Worked with Prof. Michael Fischbach-Validated an in-house LC-MS/MS based bioanalytical method to quantify 9 intracellular active metabolites, including NTPs and dNTPs-Established a gut microbiome-targeted metabolomics platform to quantify 85 microbiota-derived small molecules (eg, bile acids, SCFAs, aromatics and indoles) via LC/QTOF-MS (ESI or APCI source) and GC/MS-Optimized the protocols of sample preparation in different biological matrices, including bacterial culture, liver, serum, plasma, urine, feces, and cecal contents, for metabolomic analysis-Developed an in vitro metabolic assay pipeline to screen the metabolic function of each of 107 gut bacterial strains for rationally synthetic community design-Constructed various complex yet defined gut microbial communities (eg, strain dropout) for mechanistic study of microbe-microbe and microbe-host interactions-Led a collaborative project with Cleveland Clinic to study the biological role of single gut bacterial strain in host metabolism

Sep 2017 - Jul 2022

Research Associate

Shanghai Institute Of Organic Chemistry, Chinese Academy Of Sciences

-Worked with Prof. Wen Liu-Isolated, purified and structurally characterized a novel cysteate-containing nonribosomal peptide, cysteoamide, from Streptomyces lincolnensis via HPLC, HRMS, 1D and 2D NMR, and Marfey’s analysis-Identified the biosynthetic gene cluster of cysteoamide via bioinformatic analysis and gene knockout-Heterologously expressed, purified and functional characterized a PLP-dependent enzyme involved in the formation of the unusual cysteate unit

Jul 2016 - Jun 2017

Graduate Researcher

Shanghai Institute Of Organic Chemistry, Chinese Academy Of Sciences

-Worked with Prof. Wen Liu and Qunfei Zhao-Developed various techniques (eg, SPE, SEC, and prep-HPLC) to isolate and purify highly hydrophilic metabolites from bacterial culture, enzymatic reaction, or chemical synthesis, resulting in the identification of 11 novel biosynthetic intermediates (via NMR) in producing lincosamide antibiotics-Characterized PPL unit incorporation in lincomycin A biosynthesis through functionally studying 3 NRPS-like enzymes via a combination of techniques, such as gene knockout and site-specific mutagenesis, protein MS, and in vitro enzymatic assay-Established the distinct tailoring steps for generating the S-appendage in celestetin biosynthesis through functionally studying 3 responsible genes via in vivo genetics and in vitro enzymatic assay

Sep 2011 - Jun 2016

Graduate Researcher

Wuhan University

Wuhan, Hubei, Cn

-Worked with Prof. Yi Yu-Trained on relavant skills of molecular cloning to develop genetic tool in micromonospora

Jul 2012 - Aug 2012
Team & coworkers

Colleagues at Amgen

Other employees you can reach at amgen.com. View company contacts →

SL Stephanie Ledoux Hanes Stephanie Ledoux Hanes Colleague at AmgenLafayette, Louisiana Metropolitan Area, United States View → BA Barrah Ab Barrah Ab Colleague at AmgenJeddah, Makkah, Saudi Arabia View → AM Allison Miller Allison Miller Colleague at AmgenSimi Valley, California, United States View → ME Matt Eddy Matt Eddy Colleague at AmgenHope Valley, Rhode Island, United States View → LT Luan Truong Luan Truong Colleague at AmgenLos Angeles, California, United States View → RA Robert Ashworth Robert Ashworth Colleague at AmgenCarolina Beach, North Carolina, United States View → CH Cynthia Hsu, Ph.D. Cynthia Hsu, Ph.D. Colleague at AmgenLos Angeles, California, United States View → AO Adriana Oliveira Adriana Oliveira Colleague at AmgenSão Paulo, Brazil View → SB Simon Bannon Simon Bannon Colleague at AmgenIreland View → DC Ding Chen Ding Chen Colleague at AmgenCanada View →
3 education records

Min Wang education

Postdoctoral Fellow, Human Gut Microbiome

Stanford University

Doctor Of Philosophy - Phd, Organic Chemistry

University Of Chinese Academy Of Sciences

Bachelor Of Science - Bs, Chemical Biology

Hubei University
FAQ

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Quick answers generated from the profile data available on this page.

What company does Min Wang work for?

Min Wang works for Amgen.

What is Min Wang's role at Amgen?

Min Wang is listed as Senior Scientist at Amgen.

Where is Min Wang based?

Min Wang is based in South San Francisco, California, United States while working with Amgen.

What companies has Min Wang worked for?

Min Wang has worked for Amgen, Stanford University, University Of California, San Francisco, Shanghai Institute Of Organic Chemistry, Chinese Academy Of Sciences, and Wuhan University.

Who are Min Wang's colleagues at Amgen?

Min Wang's colleagues at Amgen include Stephanie Ledoux Hanes, Barrah Ab, Allison Miller, Matt Eddy, and Luan Truong.

How can I contact Min Wang?

You can use AeroLeads to view verified contact signals for Min Wang at Amgen, including work email, phone, and LinkedIn data when available.

What schools did Min Wang attend?

Min Wang holds Postdoctoral Fellow, Human Gut Microbiome from Stanford University.

What skills is Min Wang known for?

Min Wang is listed with skills including Microbiome, Metabolomics, Microbiota, In Vivo, Chemistry, Western Blotting, Data Analysis, and Life Sciences.

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