Structural Biologist At Nimbus Therapeutics
CurrentDesign and production of high quality protein reagents and x-ray crystallography/cryoEM structures that drive drug discovery and target validation projects.
May 2024 - Present
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Munan Shaik Email & Phone Number
Structural Biologist at Nimbus Therapeutics
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Nimbus Therapeutics
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Role
Structural Biologist at Nimbus Therapeutics
Location
Cambridge, Massachusetts, United States
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Who is Munan Shaik? Overview
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Munan Shaik is listed as Structural Biologist at Nimbus Therapeutics at Nimbus Therapeutics, a company with 49 employees, based in Cambridge, Massachusetts, United States. AeroLeads shows a matched LinkedIn profile for Munan Shaik.
Munan Shaik previously worked as Protein Engineering at Modex Therapeutics at Modex Therapeutics Inc and Associate Director at Cedilla Therapeutics. Munan Shaik holds Doctorate, Protein Crystallography, Structural Biology from Università Degli Studi Di Padova.
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Nimbus Therapeutics
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Profile bio
About Munan Shaik
Structural Biology | cryoEM | X ray crystallography | Protein Biochemist | Membrane Protein | Drug Discovery | PhD + 13 years of experience in protein science (gene to structure), crystallography, cryoEM, biochemical and biophysical assay design and development, HTS, hit finding, and validation. Leading group of scientists, CRO management, and project management. Experienced in mammalian display, affinity maturation, bispecific and multi-specific antibody design, production, engineering, and developability.
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Nimbus Therapeutics
10 roles · 14 years
Munan Shaik work experience
A career timeline built from the work history available for this profile.
Protein Engineering At Modex Therapeutics
Structure based rational design of mAb, bispecific and multispecific antibody for stability, affinity and developability.Design, Expression and purification of antigens/protein for immunization and binding studyMammalian display for affinity improvement.Bioluminate, MOE based library design and golden gate cloning platform for large scale library.
Jan 2023 - Apr 2024
Associate Director
Designed and produce recombinant proteins in bacteria, insect and mammalian system to meet project needs in assays and screenings, biophysics characterization, structural and MOA studies.Determine X-ray crystallography and cryoEM structure of targets with small molecule.Managed internal FTE and CRO FTE/FFS resources to deliver high quality protein reagents.
Oct 2021 - Dec 2022
Senior Scientist Ii
Jan 2021 - Sep 2021
Staff Scientist
Role and responsibilities:1. Lead research projects from Gene to Structure (X-tal, CryoEM) or gene to protein (High throughput assay) to support continuing research and development at St Jude Children's Research Hospital.2. Support research and development of projects from St. Jude members (Faculties).3. Establishment of world latest cutting edge.
Feb 2019 - Jan 2021
Instructor In Pediatrics
Nov 2018 - Feb 2019
Research Fellow
Role and responsibilities:1. Lead research projects in the group from Gene to Structure (X-tal, CryoEM) to support continuing research and development of HIV1 vaccine discovery and HIV1 biology.2. Developed membrane protein expression and purification and cryoEM structure determination pipeline in the group.3. Developed cell-based, fluorescence-based assay.
Jan 2016 - Nov 2018
Postdoctoral Scientist
Achievements and experiences:1. Expressed in E. coli, purified, crystallized and determined the X-ray crystallography structure of Norovirus polymerase (NVPol) in complex with duplex RNA (Primer and template) and nucleotide, and putative inhibitor.2. Structure based design of small molecule for RNA dependent RNA virus polymerase (Norovirus, HCV). 3..
2014 - 2015
~1 yr
Postdoctoral Scientist
Achievements and Experiences:1. Design Constructs, cloning, optimize expression, and purification of Minor pilin (RrgC) protein from Streptococcus pneumonia. Rational site-directed mutagenesis for successful crystallization, and used Single anomalous X-ray diffraction (SAD) techniques to determine the structure. Employed SPR to explored the binding.
2012 - 2014
~2 yrs
Doctorate Student
Achievements and Experiences:1. Design Constructs, cloning, optimize expression, and purification of Petidoglycan Deacetylase (virulence factor) from Helicobacter pylori. Determined X-ray crystallography structure, analyze enzyme activity with the different putative substrate. Using X-ray fluorescence scan determined the active site metal and quantum.
Jan 2009 - Apr 2012
Team & coworkers
Colleagues at Nimbus Therapeutics
Other employees you can reach at nimbustx.com. View company contacts for 49 employees →
IS
Ivan Sergeyev
Colleague at Nimbus Therapeutics
Greater Boston, United States
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LS
Leah Strickling
Colleague at Nimbus Therapeutics
Boston, Massachusetts, United States, United States
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JB
Julia Boffa
Colleague at Nimbus Therapeutics
Boston, Massachusetts, United States, United States
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RK
Ravi Kumaway
Colleague at Nimbus Therapeutics
Indore, Madhya Pradesh, India, India
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NT
Nicole Tritta Gallagher
Colleague at Nimbus Therapeutics
Greater Boston, United States
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SC
Samantha Carreiro
Colleague at Nimbus Therapeutics
Cambridge, Massachusetts, United States, United States
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HM
Heidi Martinez
Colleague at Nimbus Therapeutics
Puebla, Puebla, Mexico, Mexico
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SP
Sean P. Thomas
Colleague at Nimbus Therapeutics
Boston, Massachusetts, United States, United States
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BL
Bailey Lenarczyk
Colleague at Nimbus Therapeutics
Amherst, Massachusetts, United States, United States
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SE
Scott Edmondson
Colleague at Nimbus Therapeutics
Concord, Massachusetts, United States, United States
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Ivan Sergeyev
Colleague at Nimbus Therapeutics
Greater Boston, United States
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LS
Leah Strickling
Colleague at Nimbus Therapeutics
Boston, Massachusetts, United States, United States
View →
JB
Julia Boffa
Colleague at Nimbus Therapeutics
Boston, Massachusetts, United States, United States
View →
RK
Ravi Kumaway
Colleague at Nimbus Therapeutics
Indore, Madhya Pradesh, India, India
View →
NT
Nicole Tritta Gallagher
Colleague at Nimbus Therapeutics
Greater Boston, United States
View →
SC
Samantha Carreiro
Colleague at Nimbus Therapeutics
Cambridge, Massachusetts, United States, United States
View →
HM
Heidi Martinez
Colleague at Nimbus Therapeutics
Puebla, Puebla, Mexico, Mexico
View →
SP
Sean P. Thomas
Colleague at Nimbus Therapeutics
Boston, Massachusetts, United States, United States
View →
BL
Bailey Lenarczyk
Colleague at Nimbus Therapeutics
Amherst, Massachusetts, United States, United States
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SE
Scott Edmondson
Colleague at Nimbus Therapeutics
Concord, Massachusetts, United States, United States
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4 education records
Munan Shaik education
Doctorate, Protein Crystallography, Structural Biology
Xvii Bca/Ccp4 Summer School In Macromolecular Crystallography, Macromolecular Crystallography
Summer Course, Fermentation Engineering And Microarray Analysis
Master’S Degree, Biotechnology And Genetic Engineering
FAQ
Frequently asked questions about Munan Shaik
Quick answers generated from the profile data available on this page.
What company does Munan Shaik work for?
Munan Shaik works for Nimbus Therapeutics.
What is Munan Shaik's role at Nimbus Therapeutics?
Munan Shaik is listed as Structural Biologist at Nimbus Therapeutics at Nimbus Therapeutics.
Where is Munan Shaik based?
Munan Shaik is based in Cambridge, Massachusetts, United States while working with Nimbus Therapeutics.
What companies has Munan Shaik worked for?
Munan Shaik has worked for Nimbus Therapeutics, Modex Therapeutics Inc, Cedilla Therapeutics, St. Jude Children'S Research Hospital, and Harvard Medical School.
Who are Munan Shaik's colleagues at Nimbus Therapeutics?
Munan Shaik's colleagues at Nimbus Therapeutics include Ivan Sergeyev, Leah Strickling, Julia Boffa, Ravi Kumaway, and Nicole Tritta Gallagher.
How can I contact Munan Shaik?
You can use AeroLeads to view verified contact signals for Munan Shaik at Nimbus Therapeutics, including work email, phone, and LinkedIn data when available.
What schools did Munan Shaik attend?
Munan Shaik holds Doctorate, Protein Crystallography, Structural Biology from Università Degli Studi Di Padova.
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