Nahyun C. Email & Phone Number

South San Francisco, California, Us

- Developed, optimized, and onboarded a high-throughput, automated manufacturing process for IgG & VHH products in HEK293 & CHO cell lines, ensuring product quality and yield through process & quality controls - Improved process to decrease TAT by 25% & increase yields by 40% and streamlined the process by converting tubes to plates which increased throughput 2x (Announced: “Twist Express Antibodies” Jul 2024)- Presented updates on IgG projects at high-visibility meetings such as department & company all-hands

- Established fundamental analytical & experimental methods in cell culture and developed plate assays to screen for favorable cell phenotypes & to screen growth factors for media development - Represented the company with outside contractors for marketing, automation, and Benchling (LIMS) - Directed a team of 2 engineers by strategizing quarterly goals & enabled bioreactor capabilities for the startup

Emeryville, California, Us

- Designed experiments for process development & strain screening in bench-scale bioreactors, identified key process parameters & media components, and increased productivity by 10x compared to starting conditions - Led a cross-functional team through development & implementation of a HTP strain screening assay and presented regular progress updates to the client directly - Managed research associates and mentored operators in career & technical research

Berkeley, Ca, Us

- Engineered a light-responsive hydrogel that changes stiffness via modified, optogenetic protein linkers to study the effects of temporal mechanical stimulation on mesenchymal stem cell differentiation - Cloned, expressed, and purified plant proteins utilizing E. coli cultures, modified hyaluronic acid with methacrylate and thiol groups, & utilized "click” chemistry to conjugate purified proteins to hydrogel polymers- Mentored and managed a total of five undergraduate students to work as independent researcher

Berkeley, Ca, Us

- Organized weekly discussion sessions, exams, and homework problems- Taught students in both group and individual settings and refined pedagogy and oral presentation skill sets- Received Outstanding Graduate Student Instructor Award

Seoul, Kr

- Investigated patents in gas fermentation to determine value for investment in start-up companies- Researched existing methods in comparison to proposed methods- Determined regulations surrounding existing technologies and proposed technologies

Cambridge, Ma, Us

- Developed microfluidic devices that “squeeze” human cells to deliver payloads directly into the cytoplasm - Applied novel technology to tag & isolate circulating tumor cells (CTCs) from whole blood with 92% accuracy, and to reprogram primary human fibroblasts using the device with Yamanaka factors, which lead to 4x faster & 10x more iPSC cultures compared to standard protein nucleofection methods - Published four academic, peer-reviewed journal articles, received a patent, and presented at a conference (AIChE 2013)

- Utilized RT-PCR to profile AMPA and GABA receptors in RG-like cells in p8-p12 mice- Extracted neurons from the hippocampus within mouse brains via patch-clamp techniques

Doctor Of Philosophy (Ph.D.), Chemical And Biomolecular Engineering

Bachelor'S Degree, Chemical And Biomolecular Engineering

Bachelor'S Degree, Chemical And Biomolecular Engineering