Nalini Mehta Email & Phone Number

Durham, Nc

Durham, Nc

Raleigh-Durham, North Carolina Area

Investigate the therapeutic potential of AAV mediated CRISPR therapy to induce transcriptional silencing of Histone Demethylase and study its effects on Diffuse Intrinsic Pontine Glioma tumor growth and mouse survivalMentoring project involving modification of CAR T lymphocytes to improve its persistence and efficacy in Glioblastoma tumors

Atlanta, Ga

Investigating the molecular mechanisms of relapse in pediatric patients with Neuroblastoma, with special focus on using BH3 mimetic therapies to modulate the pro-survival BCL-2 family of proteins involved in stress induced apoptotic pathways.

Atlanta, Ga

Located in Atlanta, Georgia, the Georgia Institute of Technology is a leading research university committed to improving the human condition through advanced science and technology. ▬▬▬▬▬▬▬▬▬▬▬▬▬▬▬▬▬▬▬▬▬▬▬▬▬In September 2012, I joined Georgia Institute of Technology as a Research Scientist I for a project that involved finding novel nanocarrier therapy to treat brain tumors.The project was funded by Childrens’ Healthcare of Atlanta and GA Tech Brain Tumor Research funds.The results were published in Molecular Therapy Oncolytics.During my tenure in this position, I led and conducted the entire life cycle of the project including management of techniques, protocol design, troubleshooting and data interpretation. Within the documentation parameters, I recorded, compiled and analyzed complex results using charts, graphs, and presentations.As the senior leader and project manager, I supervised teams of scientists and graduate students within the laboratory setting through effective and clear communications of all policies and procedures. If you are interested in learning more about my involvement in these areas, please connect with me or request a pdf copy of the paper.

Atlanta, Ga

Emory University is a top-ranked private institution recognized internationally for its outstanding liberal arts colleges, graduate and professional schools, including the School of Medicine. It is one of the world's leading healthcare systems and has on an average $572 million in research funding.▬▬▬▬▬▬▬▬▬▬▬▬▬▬▬▬▬▬▬▬▬▬▬▬▬▬ As a Research Associate at Emory University, I planned, designed and conducted the majority of the experiments and protocols in a viral super-antigen project. This particular project involved the overexpressing and purifying of a potential superantigen protein originally from a murine gamma herpes virus in a mammalian system. Subsequently, the purified protein was then used in vitro and in animals to check for its superantigen properties. I managed the full scope of the research operations including the monitoring of laboratory processes, studying the biological mechanisms, as well as optimization, troubleshooting, and quality control measures. I was also responsible for recording, analyzing, interpreting and presenting the final results. I also mentored students and postdoctoral fellows in the pursuit of desired results of the project.Results ⇨ purification and collection of large amounts of protein for conducting in vitro and in vivo testing, which, through the processes and procedures of the project, showed that the protein worked based on our hypothesis as a super antigen. The technologies used in our efforts were optimized and can be reproduced/used by other researchers.Connect with me for more information.

Greater Atlanta Area

In 2008, I joined the Georgia Institute of Technology as a Research Scientist I. In this role, I collaborated with a team of scientific researchers on a project involving the destruction of radio-nuclide using marine bacteria. In pursuit of excellence in scientific processes and procedures, including data collection and enhanced delivery of results, I worked directly with the team to ensure completion of the research project.During my tenure with the university, I also served as the Interim Instructor for the Fall 2009 “Introduction to Microbiology” course. In this role, I developed course lectures, designed and maintained the course syllabus, created study materials, and provided personalized mentoring for students under my tutelage.

Pittsburgh, Pa

The Center for Genomic Sciences (CGS) is a comprehensive and flexible research facility designed to investigate a broad range of medically and surgically relevant problems using cutting-edge molecular genetics and bioinformatics techniques▬▬▬▬▬▬▬▬▬▬▬▬▬▬▬▬▬▬▬▬▬▬▬▬▬▬In 2004, I joined the Center for Genomic Sciences as a Research Associate. In this role I conceived, designed and implemented projects to study pathogenesis of clinical strains of biofilm bacteria such as Streptococcus pneumoniae, Staphylococcus epidermidis, Pseudomonas aeruginosa and Haemophilus influenzae. In addition, I constructed mutant strains and transcriptional regulation strains in challenging pathogens, study the significance of various genes in pathogenesis and biofilm formation using animal studies, histology, FISH and biofilm studies.I also used protein purification techniques and Western blotting to investigate differences in the translation of proteins in S. pneumoniae wild type and mutant strains.In a project management and leadership capacity, I led research projects, worked diligently to ensure accuracy, completeness, and verifiability of results, and effectively managed people, processes, and timelines to ensure seamless execution. I also trained and supervised research fellows, graduate students, medical students and technicians on Microbiology and Molecular Biology techniques.

Athens, Georgia Area

The University of Georgia, a land-grant and sea-grant university with statewide commitments and responsibilities is the state's oldest, most comprehensive, and most diversified institution of higher education.▬▬▬▬▬▬▬▬▬▬▬▬▬▬▬▬▬▬▬▬▬▬▬▬▬▬As a Postdoctoral Research Fellow at UGA, I conceived, designed and implemented studies related to unraveling the mechanism of pathogenesis in Helicobacter pylori and H. hepaticus. In addition, I worked on two separate NIH grants for individual research programs, and documented, summarized and published research findings in conferences and peer-reviewed journals.During my tenure at the university, I also served as trusted mentor and supervisor within the Microbiology Department.

Mumbai Area, India

Johnson & Johnson is an American multinational medical device, pharmaceutical, and consumer packaged goods manufacturer founded in 1886.▬▬▬▬▬▬▬▬▬▬▬▬▬▬▬▬▬▬▬▬▬▬▬▬▬▬In my role as a Microbiologist at Johnson & Johnson, I performed as a Quality Assurance Specialist with GMP and GLP certifications, and was responsible for designing, developing, and validating test methods for on-and off-site hospital and consumer products using advanced testing methodologies.Other primary responsibilities included the establishment and maintenance of QA procedures and controls, ensuring that all performance parameters were continually met to drive ongoing improvement initiatives for organization including SOP compliance and safety and environmental regulations.Within a data management capacity, I identified significant trends using analytical skills, and reported them regularly to management, as well as cross-functional teams. In the performance of my duties, I consistently met pressing deadlines in support of QA and R&D functions.

Doctor Of Philosophy (Ph.D.), Microbiology

Activities and Societies: I received a Research Assistantship award for 4 years throughout completion of my PhD.Dissertation Topic.

Master Of Business Administration (M.B.A.)

Activities and Societies: Graduated with Honors while still employed as a Research Scientist I at Georgia Institute of TechnologyEg. MBA.