Neel Deferm Email & Phone Number

Engaged in the development of mechanistic ADME models within the Simcyp simulator with an emphasis on advancing PBPK simulations in the paediatric, pregnancy and postpartum populations.

Providing services in physiologically-based pharmacokinetic modeling.

Contributed to physiologically-based pharmacokinetic modeling in the IMI ConcePTION project—a pan-European collaboration uniting 88 organizations across 22 countries. Our research focused on establishing a non-clinical testing platform for predicting drug concentrations in human breast milk, enhancing safety information for medications used during pregnancy and breastfeeding.

Leuven

Investigated drug-induced cholestasis using various in silico and in vitro methodologies. The doctoral thesis was entitled 'Drug-induced cholestasis: in vitro detection and mechanistic insights', and was endorsed by a fellowship of the Flemish Agency for Innovation through Science and Technology (FWO-SB).

San Francisco En Omgeving, Verenigde Staten

Developed a physiologically-based bile acid disposition model using PK-Sim® as modeling platform. The model was informed with in-house generated transporter kinetic data.

Neerpelt

Interned at the Molecular Endocrinology Laboratory. Explored to what extent androgen regulated the insulin receptor and the glucose transporter 4 (GLUT4) in skeletal muscles.

Doctor Of Philosophy - Phd, Pharmaceutical And Pharmacological Sciences

Master'S Degree In Drug Development, Pharmaceutical And Pharmacological Sciences

Bachelor'S Degree, Pharmaceutical And Pharmacological Sciences