Neil Mcdonald Email & Phone Number

I am a Principal Group Leader and Head of the Signalling and Structural Biology Laboratory at the Francis Crick Institute. I have over 25 years experience running a research laboratory within a Biomedical Research Institute (Francis Crick Institute / London Research Institute, CR-UK / Imperial Cancer Research Fund). My laboratory is interested in visualizing kinase-driven signalling assemblies involved in both trophic support, cell adhesion and cell polarity. We use structural biology, biochemical and biophysical techniques to explore the molecular mechanisms underpinning protein kinase architecture, regulation and substrate-targeting. I have also driven both small molecule and biological modulator programmes against protein kinases to target their pathological roles in human disease. I am also a Professor of Structural Biology in the Department of Biological Sciences, Birkbeck College, London.

Listed skills include Molecular Biology, Biochemistry, Life Sciences, Protein Chemistry, and 6 others.

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  University Of London