Pavithran Krishnan Email and Phone Number

Conducted High-Performance Liquid Chromatography (HPLC) to quantify and determine technical ingredient concentrations in pesticidal and herbicidal products.Performed Inductively Coupled Plasma Optical Emission Spectroscopy (ICP OES) for the analysis of heavy metals such as Fe, Pb, Ar, and Sb in product samples.Conducted physical tests such as sieving, viscosity measurement, and emulsion tests to ensure products met physical specifications and quality standards.Performed regular Particle Size Distribution Analysis using The Bettersizer ST to ensure consistency, uniformity, and reproducibility of pesticide formulations.Analysed glyphosate and ammonia concentrations in product samples using UV spectrophotometry to ensure regulatory compliance.Collaborated closely with the production team to address and rectify quality issues, adjusting failed or rejected products.Maintained accurate records of analytical data, test results, and quality control documentation in compliance with regulatory requirements.

Developed solid oral dosage forms specializing in oncology products, achieving compliance with stringent OEB Level 4 and above standards.Conducted routine testing using Dissolution Testers (Electrolab), ensuring consistent adherence to established protocols and regulatory standards for various solid oral dosage forms.Utilized advanced analytical techniques, including HPLC analysis, to precisely measure drug release profiles, resulting in formulations that consistently met regulatory specifications.Demonstrated expertise in calibrating and operating analytical instruments like Powder X-ray diffractometer, Differential Scanning Calorimeter, Thermogravimetric Analyser, Dynamic Vapour Sorption Analyser, Hot-Stage Microscope, and Malvern Mastersizer 3000 Particle Size Distribution Analyser.Played a pivotal role in maintaining product stability and integrity by implementing precise moisture analysis techniques such as the Karl Fischer titration method.Led formulation decoding efforts for innovator drug products and conducted comprehensive solid-state/material characterization studies, enhancing understanding and ensuring product stability.Contributed to the development and validation of analytical methods, particularly for PSD and PXRD, ensuring compliance with rigorous GMP, GLP, QMS, and risk management standards.Supported led patent filings and secured approvals from regulatory authorities such as USFDA and DCA Malaysia, demonstrating adept project management and regulatory compliance skills.Implemented continuous improvement initiatives resulting in enhanced processes, reduced waste, and increased operational efficiency, thereby contributing to organizational excellence in pharmaceutical development.

Conducted physical tests on Glucoxit tablets from batch production using DisiTest 20 Disintegration Tester, Friabilitator USP Electrolab, and Tablet Testing System PTB 311E for tablet thickness, diameter, and hardness.Performed Flame Atomic Absorption Spectroscopy on B1 Haemo-sol Tablet and uniformity testing on 'Methazine' tablet using HPLC in the Quality Control Department.Executed routine testing of deionized water (conductivity & Total Organic Carbon) using Water Quality Meters Horiba LAQUA EC220 and Sievers M9 Laboratory TOC Analyzer to ensure compliance with standards and analysis requirements.Responsible for operating and maintaining water treatment plants, including purification systems for different applications. Conducted manual backwash procedures, hot water sanitization, flush, and sterilization for purified water, water for injection, HAEMO water, and deionized water systems.Ensured proper functioning and cleanliness of water treatment systems, following protocols and regulatory requirements.Engaged in the operation of a wastewater treatment plant, specifically a Membrane Bio-Reactor (MBR) tank. Conducted parameter testing including COD (Heating block NANOCOLOR VARIO C2 & Compact photometer PF 12Plus), Suspended Volume For 30 Minutes (SV30), Total Suspended Solids (ODEON X Handheld Water Quality Meter), and pH of the incoming wastewater from the treated tank.Acquired hands-on experience in various aspects of pharmaceutical manufacturing, including raw material dispensing, granulation, sieving, milling, tableting, encapsulation, and coating processes.Actively participated in the production cycle, conducting spot checks to ensure batch products met quality standards. Maintained accurate production records by regularly recording machine output ratios within the production department.