Vivian Hsu Email & Phone Number

Melbourne, Victoria, Australia

Sydney, Australia

• Utilized Python and Cloud Computing to implement bioinformatic techniques for my repeat expansion detection analysis on 27 TB of patients’ Whole Genome Sequencing data• Developed the pipeline of systematic methodology to investigate the potential genetic cause of Spontaneous Coronary Artery Dissection (SCAD) by using bioinformatics and statistical techniques• Observed the high concordance of repeat extensions occurred in FMR1 gene region identified by TREDPARSE and ExpansionHunter… Show more • Utilized Python and Cloud Computing to implement bioinformatic techniques for my repeat expansion detection analysis on 27 TB of patients’ Whole Genome Sequencing data• Developed the pipeline of systematic methodology to investigate the potential genetic cause of Spontaneous Coronary Artery Dissection (SCAD) by using bioinformatics and statistical techniques• Observed the high concordance of repeat extensions occurred in FMR1 gene region identified by TREDPARSE and ExpansionHunter Show less

Sydney, Australia

Acted as biostatistician for Drop Bio Pty Ltd, to perform R/analytical programming and Python, and manage genetic sequencing data. Developed methodology of building statistical model between genetic variant and diseases in order to predict the probability of diagnosis of certain diseases• Converted and merged data from a wide variety of sources - 1000 Genome Projects, Hapgen2 and plink data• Simulated genotype variants with 1000 controls and cases to create analytical datasets for… Show more Acted as biostatistician for Drop Bio Pty Ltd, to perform R/analytical programming and Python, and manage genetic sequencing data. Developed methodology of building statistical model between genetic variant and diseases in order to predict the probability of diagnosis of certain diseases• Converted and merged data from a wide variety of sources - 1000 Genome Projects, Hapgen2 and plink data• Simulated genotype variants with 1000 controls and cases to create analytical datasets for training and testing• Performed analytical tasks using R/Rstudio, Python, and Shell• Assisted in developing analytical methodology for the further analysis with routinely collected from research participants• Created and maintained documentation to document process and data quality issues. Show less

Sydney, Australia

• Utilized Python, Shell and R on cloud computing to identified high prevalence of patients with serous ovarian cancer having mutations in TP53 • Managed 12 TB of Ion Torrent Targeted Deep Sequencing data stored in NCI using SQL, Python and R to visualize the datasets to track the features of datasets performed by Ion Torrent Variant Caller• Publication: Q. Wang, V. Kotoula, P.-C. HSU, K. Papadopoulou, J. W. K. Ho, G. Fountzilas, E. Giannoulatou. Comparison of somatic variant detection… Show more • Utilized Python, Shell and R on cloud computing to identified high prevalence of patients with serous ovarian cancer having mutations in TP53 • Managed 12 TB of Ion Torrent Targeted Deep Sequencing data stored in NCI using SQL, Python and R to visualize the datasets to track the features of datasets performed by Ion Torrent Variant Caller• Publication: Q. Wang, V. Kotoula, P.-C. HSU, K. Papadopoulou, J. W. K. Ho, G. Fountzilas, E. Giannoulatou. Comparison of somatic variant detection algorithms using Ion Torrent targeted deep sequencing data. BMC Medical Genomics 12.9 (Dec. 24, 2019) p. 181. 2019 Show less

Taiwan

• Examined new IC chips• Utilized C programming to test IC chips and examined the quality of chips under certain conditions based on customers’ requirements • Utilized Microsoft Excel and Rstudio for data analysis on IC chips testing results and SQL for data warehousing

Master'S Degree, Health Data Science, Master With Excellence

Bachelor'S Degree, Bioinformatics

Activities and Societies: UNSW TSA, UNSW WOMEN IN ENGINEERING, UNSW DIY SOCIETY, UNSW ADVANTURE SOCIETY

Foundation Degree, Physical Sciences

Activities and Societies: UNSW DEBATING SOCIETY