Responsible for the biocompatibility evalution of implants and instruments (new product developments (NPDs as well as existing products) according to ISO 10993 and ISO/TR 15499. Involved in the sterilization and resterilization evalution of implants and instruments as well as in the writing of GSOPs and local work instruction for biocompatibility and sterilization. Scientifc advisor for biomedical question.

In charge of the development and maintenance of a physical parameter reference database that is used worldwide for safety evaluations of wireless electronic devices such as cell phones or MRIs.

I studied the function of the putative RNA Helicase HELZ using molecular biological, biochemical and immunological tools. The following are my main scientific achievements:1. The putative RNA helicase HELZ promotes protein translation and cancer cell proliferation.• I found that depletion of HELZ from MCF7 (human breast adenocarcinoma) cells or HeLa (cervical cancer) cells results in a significant decrease of cell proliferation. • HELZ plays a role in translation initiation and the phosphorylation of the ribosomal protein S6, which is a component of the mTOR signaling pathway. This pathway is known to be dysregulated in many human cancers. 2. Conserved LxxLAP motifs within a protein are not a prerequisite for oxygen-dependent regulation.• Even though the site of oxygen-dependent regulation in the HIF protein is found within a LxxLAP protein sequence motif, in other proteins it is not. Therefore, a protein sequence screen for this motif does not help to find novel proteins that play a function within the hypoxic microenvironment of a tumor.

Studied the effect of cigarette smoke on Eosinophil biology and discovered that cigarette smoke aggrevates Asthma by activating eosinophils to release pro-inflammatory mediators.

Identified salt requirement of Halanaerobium praevalens and Salinibacter for optimal growth (0.4-0.5 M and > 3M respectively). Salinibacter has the highest chloride concentration requirement of all eubacteria organisms.