Raphael Williams Email & Phone Number

Gaithersburg, Maryland, United States

Primarily focused on process characterization using QbDPerformed Risk Assessments.Drafted DOE protocolsActed as PiP to technical teams on DOE execution daysAnalyzed dataDrafted reports used in control strategyCross-function/collaboration with QA to verify data and executionPresented data to client as well as DOE setup and analysis methodologyClients have ranged from preclinical transition to Phase 1 to Phase 2/3 transition to commercial

9605 Medical Center Dr #200, Rockville, Md 20850

Worked on build out of new lab space when company moved from 9605 Medical Center Drive to 9713 Keywest Ave location. Was responsible for cleaning up the lab, packing equipment from 9605 medical center dr and decommissioning the radiological lab. Collaborated with vendors from VWR and ThermoFisher on purchasing BSCs, incubators, disposables and flooring at the Keywest Ave Site.Performed Process Characterization post FDA Hold in 2017 to get invossa off FDA hold and into the clinic by working with Dr. Kwangwook Ahn and consultants to retrofit its old process into a QbD Process and demonstrate the updated process was in control at the current CMO Vs not being in control at another CMO. Departed shortly before dosing began at US sites to gain more practice specifically in QbD and Process Characterization. Assist in scale-up of Invossa with CROs for Phase III Clinical trial and GMP manufacturing for potential market launch. Review CRO Data with PI.Assist in QbD process characterization including establishing design space through DOE, where experimental data will be used in multivariate regression analysis Participate in meetings between CROs, handle samples and shipping between TissueGene and CRO/CMO.Participate in QC tests for Invossa: qPCR, ELISA and Colorimetric AssaysParticipate in surface marker characterization of in house cell lines. Perform raw materials and reagent inventory for TissueGene experiments.Conduct ordering raw materials and reagents for scale up experiments with CROs.Maintain correspondence with contacts at CROs and materials vendors. Check out the company's paper!http://www.oarsijournal.com/article/S1063-4584(15)01057-2/abstract

Rockville, Maryland, United States

Associate level researcher working on method validation, primarily doing western blots as a QC assay for a potential MRSA vaccine.

Pittsburgh, Pennsylvania

I am responsible for sample preparation on the Molecular end of the process. I also care for and bank some mammalian cell lines expressing recombinant proteins.I maintain our flow-cytometer as well as our plate reader/Imager.Most recently, I have been working on optimizing our CFTR assay in flow.I also keep inventory of reagents.

Jacobus, Pa

I assisted in vitro preparation of aptamers ( small nucleic acid polymers with antibody like behavior and nanomolar affinity.) In addition, I prepared aptamers against proteins and whole cells using SELEX, as well as sample prep for illumina next generation sequencing.I Consistently demonstrated aseptic technique while working with mammalian cells and worked in a clean room environment. I Followed SOPs and revised SOPsMy last task was working with workflow software and bioinformatics tools to perform sequence analysis of Illumina FASTQ data.

Clarion University

Cultured cellsplanned assaysfollowed SOPs and wrote some protocolsMaintained and operated the Deltavision RT Fluorescence microscope.

Checked out books for patrons Confirmed the status of books also keeping them in order,Used file maker pro software I assisted the library in keeping an accurate list of active patrons.

Bachelor Of Science (Bs), Molecular Biology With Minors In Mathematics And Nanotechnology

I worked with C. Violaceum as an undergraduate researcher to elucidate protein-protein interactions in its Type II Secretion system.

Associate Of Science (As), Biology, General

Education record

Education record

Education record