Reece Mabbett Email & Phone Number

Birmingham, England, United Kingdom

Kobe, Hyogo, Japan

Oxford, England, United Kingdom

Assisted research led by Professor Sarah Gilbert & Associate Professor Teresa Lambe as part of the Jenner Institute and Oxford Vaccine Group developing novel outbreak pathogen vaccines, including occasional contribution to the preclinical programme. Research spanned across both humoral and cell-mediated immunology in accordance to GCP standards using serum, plasma, and isolated fresh & frozen PBMCs from volunteers participating in ChAdOx COVID-19 (and other outbreak pathogens) related trials.Laboratory techniques/responsibilities:• PBMC isolation from adult and paediatric whole blood• Independently managed temperature-controlled storage and transit of various blood components• IFNy generating T-cell ELISpot (using fresh and frozen PBMCs)• Synthetic peptide pool preparations and large scale plating for multiple emerging pathogen clinical trials including SARS-CoV-2 (multiple variants), Ebola, Rift-Valley Fever & Yellow Fever Virus• In-house ELISA for anti-nCoV spike IgG• Mammalian cell culture (HEK293, A549 & human PBMCs)• Contributed to optimisation & introduction of a CD8+ cytotoxicity killing assay • Trained MSc/DPhil/MD students & external collaborators for various immunology-focused projects• Management & production of clinical trial databases and sample inventories in collaboration with multiple NHS Trust Hospitals

Daegu, South Korea

Cultural exchange and English teaching position across 3 public schools in Daegu, South Korea. • Independently taught students aged between 6-19 in classes ranging from 2-30 students.• Developed and managed school curriculums and cultural/community-focused events.• Assessment & evaluation of students' academic performance.• Attended a Korean language academy & gained intermediate proficiency.

Birmingham, United Kingdom

A blended role supporting HCPC-registered biomedical and clinical scientists in the Clinical Immunology Service (QE Hospital) while also leading the experimental workload for a phase III clinical trial based in the Institute of Immunology & Immunotherapy. The TEAMM trial primarily investigated interactions between the triad of (i) Myeloma disease activity, (ii) Immune-competence (iii) Infections and Health Care-Associated Infections to stratify patients for risk of infection, guide use of prophylactic antibiotics and improve response to anti-myeloma therapies.Laboratory techniques/responsibilities:• A wide range of ELISAs (both manual and automated) for markers of immune competence and inflammation using serum, plasma, saliva and tears e.g. sIgA, procalcitonin, calprotectin, elastase, lactoferrin & MMP-9 activity• Luminex Multiplex immunoassay (27-plex cytokine & 19-plex bacterial and viral Ab microsphere panels) • WBC isolation using layered gradients & MAC magnetic isolation kits• Specialist neutrophil analysis e.g. ROS production, DNA NET fluorescence, IL-8 chemotaxis chamber • Viral immunity studies including Ig subclasses for Influenza vaccine, CMV, EBV• Managing and generating large-scale clinical trial databases across multiple sites• Assisting NHS Clinical Immunology Service with various routine and specialist diagnostic assays• Independent management of 7000+ samples inc serum, plasma, whole blood, saliva, tears, urine & CSF• Blood donor recruitment & Phlebotomy

St Thomas' Hospital, Westminster, London

An IBMS accredited placement year during my undergraduate degree where I actively provided technical and administrative support to HCPC registered Biomedical and Clinical Scientists across the Haemostasis & Thrombosis department (UKAS and CPA accredited) across Guy's & St Thomas NHS Trust Hospitals.Responsibilities/Notable Experiences:• Specimen reception, preparation & storage (whole blood, serum, plasma, urine, saliva & CSF) • Analyser maintenance, calibration and troubleshooting.• Manual & automated diagnostic assays e.g. FVIII, Antithrombin, Protein C & routine coagulation screens (PT, APTT, Fibrinogen, D-dimer, 50:50 Mixing studies)• Specialist diagnostic tests including Lupus Anticoagulant (LA) i.e. RVVT, ET, TT• Assay development & QC (PC clotting activity & VKOR metabolites)• Produced patient information documents concerning platelet/bleeding assessments • Rotated throughout a variety of laboratories & outpatient settings including: Nutristasis, Automated Chemistry, Immunophenotyping, Special Haematology, Molecular & Routine Haemostasis, Anticoagulation & Haemophilia Clinic fulfilling a portfolio of work-based competencies and case-based discussions in a similar fashion to the NHS Scientist Training Programme. • Experienced with the following automated analyser platforms: Sysmex CS2100i, Werfen ACL Top300/500, Dynex DS2, PFA-100, Chronologue, KC10/KC4, Abbot Architect • Experienced with the following software packages: Microsoft Office, GraphPad, Q-Pulse, Data8, PathNet, ImageJ & SPSS

Master'S Degree, Clinical Sciences - Histocompatibility & Immunogenetics

Bachelor Of Science - Bsc, Biomedical Science (Ibms Accredited), First Class Honours

Activities and Societies: Anthony Nolan (Surrey Marrow) Donor Registration Volunteer