Saksin Life Sciences is R & D based at Chennai currently involved in the development of novel biologics against eye diseases. Was actively involved in setting of the facility and Analytical/ Bio analytical Lab. Key responsibilities include literature search ,experiment designing ,preparing scientific discussions and presentations. Responsible for assay development of antibody based molecules, cell based assays, Biophysical and Biochemical characterization. In process related impurities. Method… Show more Saksin Life Sciences is R & D based at Chennai currently involved in the development of novel biologics against eye diseases. Was actively involved in setting of the facility and Analytical/ Bio analytical Lab. Key responsibilities include literature search ,experiment designing ,preparing scientific discussions and presentations. Responsible for assay development of antibody based molecules, cell based assays, Biophysical and Biochemical characterization. In process related impurities. Method development and validation for ligand binding assay as per the regulatory guidelines. Show less

Actively working in Invitro pharmacology in various ongoing Drug Discovery programs.Key responsiblities include Literature search and desigining experiments .Standardization of biochemical( enzyme assays )using various platforms like TR-FRET,Fluorescence etc as per programme requirements .Screening of NCEs .Standardization of Cell based assays ,CYP assays,Microsomal Stability ,Plasma conversions ,Solubility assays.Western blots to study the effect of molecules on downstream… Show more Actively working in Invitro pharmacology in various ongoing Drug Discovery programs.Key responsiblities include Literature search and desigining experiments .Standardization of biochemical( enzyme assays )using various platforms like TR-FRET,Fluorescence etc as per programme requirements .Screening of NCEs .Standardization of Cell based assays ,CYP assays,Microsomal Stability ,Plasma conversions ,Solubility assays.Western blots to study the effect of molecules on downstream pathways.ELISAs,,Cell based ELISAs .Working on biotransformation of NCEs.Mentored and trained people on the above mentioned platforms Show less

Was actively involved in setting up of Proteomics facilities at TCGA. Standardization of various Techniques involved in Proteomics & Biomarker Discovery.Standardized 2D Gel electrophoresis from various bacteris,fungus,plants,biological fluids(Plasma ,Serum,saliva etc), cell lines.etc.,DIGE , Peptide profiling using clinprot beads and dynabeads Standardization of techniques involved in Protein Identification & Sequencing using MALDI TOF-TOF & LCMS-MS-MS .Depletion of high abundant… Show more Was actively involved in setting up of Proteomics facilities at TCGA. Standardization of various Techniques involved in Proteomics & Biomarker Discovery.Standardized 2D Gel electrophoresis from various bacteris,fungus,plants,biological fluids(Plasma ,Serum,saliva etc), cell lines.etc.,DIGE , Peptide profiling using clinprot beads and dynabeads Standardization of techniques involved in Protein Identification & Sequencing using MALDI TOF-TOF & LCMS-MS-MS .Depletion of high abundant proteins from PlasmaPreparation of SOPS/Protocols.Interact with customers and provide solutions as per the requirement.Actively worked in Biomarker projects involved at TCGA.Trained Juniors and Trainees for disseration projects Show less

Worked as Project Fellow in DBT funded project entitled “Development of Monoclonal antibody(s) against Troponin T for an Immunoassay” from 16.10.2000-30.11.2002 with Institute of Genomics and Integrated Biology (formerly CBT), Delhi.Worked on protein purification using Ion exchange chromatography,Elisas,Western blots,Molecular biology Animal tissue culture.Provided Training to summer Trainees