Robert Babb Email & Phone Number

Tarrytown, New York

• Director (2014-Present)Associate Director (2011-2013)Sr. Staff Scientist (2008-2010)Staff Scientist (2005-2007)Scientist (2002-2004)
• Analysis and selection of therapeutic antibody candidates based on in vitro primary screening data and antibody sequence
• Supervised automated high-throughput platform to clone antibody variable domains from B cells isolated from immunized VelocImmune® mice
• Development of vector system and Chinese Hamster Ovary (CHO) cell line host capable of expressing antibody titers up to 2 g/L in bioreactors
• Cloning and characterization of a novel genomic locus from Chinese Hamster Ovary (CHO) cell lines capable of site specific recombination

Summit, NJ

• Characterization of the transcriptional activity and functional interactions of a PPARγ coactivator using cell culture and protein-protein interaction techniques
• Examination of the transcriptional regulation of the peripheral cholesterol transporter ABCA1 by the insulin signaling pathway and forkhead transcription factors using reporter gene assays and Taqman RT-PCR
• Coordinated the formation of a monthly postdoctoral seminar

Cold Spring Harbor, New York

• Determined the contribution of the Oct-1 POU-domain linker in DNA binding and coregulator association using electrophoretic mobility retardation assays
• Identified a novel DNA-binding domain in the viral transactivator VP16 using site-directed mutagenesis of the structurally determined VP16 core domain
• Characterized the molecular interactions of the B-cell specific transcriptional coregulator OCA-B with the Oct-1 POU DNA-binding domain

Baltimore, Maryland Area

• Optimized PCR amplification conditions for microsatellite, di-nucleotide repeat polymorphisms from patient samples for a multicenter schizophrenia linkage study

Doctor Of Philosophy (Ph.D.), Genetics

Master’S Degree, Biology, General

Bachelor’S Degree, Biology, General