Robert Czerwinski Email & Phone Number

Biochemist/Enzymologist with 15+ years of diverse drug discovery experience in the pharmaceutical industry. Involved in drug the progress from early exploratory to late development. Successful in the environment of both the large pharmaceutical as well as biotech startups. Part of the team that developed a small molecule antagonist for HIF2a, which is now in Phase III clinical trials for clear cell renal cell carcinoma and Phase II for treatment of Von Hippel-Lindau Syndrome. Expert in:- Development of biochemical, biophysical and cell-based assays.- Determination of the kinetic and catalytic mechanism of enzyme targets.- Development and troubleshooting of enzyme assays for use in HTS as well as in enzyme characterization.- Able to manage multiple projects and people in a fast-paced environment. - Expertise in understanding the mechanism of drug-target interaction and the identification of non-specific inhibitors in the early stages of the drug development process.- Experience with robotic liquid handling and lab automation- An understanding of the protein purification process- Experience in the use of many data fitting programs such as DynaFit, Graph Fit and Sigma Plot

Listed skills include Drug Discovery, Assay Development, Biochemistry, High Throughput Screening, and 4 others.