Robin Pearce Email & Phone Number

• Development of deep learning methods to target formerly "undruggable" diseases through circular RNA therapeutic design

• Development of deep learning methods for protein/RNA folding and design
• Responsible for mentoring undergraduate and graduate thesis projects

• Development of deep learning methods for protein/RNA structure prediction and design
• Development of physics & statistical methods for protein structure prediction and design
• Design and experimental validation of therapeutic proteins targeting important pathways involved in cancer and COVID-19
• Served as web master for the Zhang Lab server system, which has been used by more than 160,000 users from 158 countries and territories

• Development of imaging technology for in vivo dosimetry during external beam radiation therapy
• Cherenkov radiation detection using silicon photomultipliers
• Software design for Monte Carlo verification of radiation therapy treatment plans

• Creation of paper-based diagnostic tests for tuberculosis and temperature-dependent kill switches for bacteria
• Leader of public outreach team
• Received silver medal recognition at the International Genetically Engineered Machine (iGEM) competition in 2016 and bronze medal recognition in 2017

• Novel HSP90 small molecule inhibitor discovery and pharmacological profiling
• Performed viability assays to determine the EC50 values of numerous novel HSP90 inhibitors
• Investigated the synergistic effect of combination therapy through Western blot analysis of proteins involved in the mTOR pathway, heat shock response, translation initiation, EMT transition, and apoptosis
• Carried out quantitative RT-PCR to assess the efficacy of combination therapy in attenuating the unfolded protein response

Doctor Of Philosophy - Phd, Computational Medicine And Bioinformatics

Master'S Of Science In Engineering, Biomedical Engineering

Master'S Of Science, Biological Chemistry

Bachelor'S Degree, Biomedical Engineering, Graduated Summa Cum Laude