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Robert Somerville is listed as Scientist III at Alba Therapeutics, a company with 23 employees, based in Montgomery Village, Maryland, United States. AeroLeads shows a work email signal at albatherapeutics.com and a matched LinkedIn profile for Robert Somerville.
Robert Somerville previously worked as Scientist II at Alba Therapeutics and Postdoctoral Research Associate at Cleveland Clinic. Robert Somerville holds D.Phil, Molecular Cell Biology from University Of York.
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Twelve years of combined academic and industrial experience in understanding the molecular basis of human disease, in the areas of parasitology, oncology and autoimmunity, with an emphasis in the areas of diagnostics, and drug delivery and discovery.Specialties: Purification of recombinant proteins.Antibody staining, ELISA, IHC, IF and basic histologyHighly skilled in molecular biology, including PCR, cloning, transfection, RNAi and shRNA and library construction.In vivo analysis of transgenic animals including embryonic development, skilled in small animal handling.Independent in designing and executing experiments, data analysis and preparing manuscripts for publication. Strong communication skills.
Listed skills include Cell, Molecular Biology, Cell Culture, Protein Chemistry, and 15 others.
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Led a project that successfully identified the target for a drug delivery and vaccine adjuvant that is based on zonula occludens toxin from Cholera.Identified potential targets for Larazotide acetate, a phase II clinical candidate for the treatment of celiac disease, using a number of molecular screens. Involved in the identification of the cell signaling.
Produced and purified recombinant versions of the cholera toxin, zonula occludens toxin.Established novel in vitro assays for use in the discovery and SAR of new epithelial permeability agonists that have can be used as drug delivery agents and vaccine adjuvants, and epithelial permeability antagonists that can be used as therapeutics in autoimmune.
Identified novel metalloprotease family members, ADAMTS9, ADAMTS10 and ADAMTS20 as well as a novel splice variant of ADAMTS7.Established a mammalian expression system for the production of recombinant ADAMTS enzymes and their individual domains under serum free culture conditions.Purified the recombinant proteins by a combination of metal ion affinity.
Established an in vitro culture system of mouse metatarsals which allows elucidation of the precise cause of dwarfism in MMP14 knockout miceInvestigated the potential role of MT1-MMP in growth factor imbalances using an in vitro metatarsal culture systemUsed peptide affinity purification techniques to show that the cytoplasmic tail of MT1-MMP interacts.
Identified an unbalanced translocation in a glioblastoma multiforme (brain tumor) cell line and determined that LGI-1 was inactivated by the translocation using a positional cloning strategy.Utilized a yeast two-hybrid screen to identify protein-binding partners for the myeloproliferative disease gene ZNF198.
Activities and Societies: Member of The British Society For Parasitology Identified mechanisms by which cattle lymphocytes infected with.
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Robert Somerville works for Alba Therapeutics.
Robert Somerville is listed as Scientist III at Alba Therapeutics.
AeroLeads has found 1 work email signal at @albatherapeutics.com for Robert Somerville at Alba Therapeutics.
Robert Somerville is based in Montgomery Village, Maryland, United States while working with Alba Therapeutics.
Robert Somerville has worked for Alba Therapeutics and Cleveland Clinic.
You can use AeroLeads to view verified contact signals for Robert Somerville at Alba Therapeutics, including work email, phone, and LinkedIn data when available.
Robert Somerville holds D.Phil, Molecular Cell Biology from University Of York.
Robert Somerville is listed with skills including Cell, Molecular Biology, Cell Culture, Protein Chemistry, Elisa, Pcr, Transfection, and Immunohistochemistry.
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