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• Deep knowledge of peptide structure-activity relationships and novel amino acid chemistry • Broad understanding of organic and biological chemistry including nucleic acid and saccharide synthesis• Key driver of late-stage discovery and API process development of the approved macrocyclic peptide drug zilucoplan/Zilbrysq (RA101495) from phase 1 through establishment of phase 3 and commercial processes.• Clear and effective oral and written communicator and a builder of high-performance teams.• Outsourcing expert with a history of successful CDMO/CRO collaboration and supply chain assurance.• A natural leader, mentor, and motivator who thrives in environments requiring collaborative problem solving while managing direct reports and company partners in cross-disciplinary scientific teams. • Innovation focus with consistent patenting and high-impact publications. Fellow, National Academy of Inventors
Newco
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Director, Chemistry And PlatformNewco Nov 2024 - Present
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Director, Medicinal ChemistryBicycle Therapeutics Apr 2022 - Aug 2024Cambridge, England, GbInnovative medicinal chemistry of immuno-oncology bicyclic peptide conjugates advancing partner and internal programs -
Director, Discovery ChemistryPepgen Jun 2021 - Apr 2022Boston, Massachusetts, UsStrategized medicinal chemistry and in vitro screening cascade for peptide-oligonucleotide conjugates Established initial lab operations for PepGen and designed permanent chemistry lab buildout -
Director, Technical Operations At Ucb / Ra PharmaUcb Apr 2020 - May 2021Brussels, BeAuthored drug substance sections of worldwide regulatory submissions and provided rapid and detailed responses to regulatory agencies to assure no delay in clinical programs -
Director, Technical OperationsRa Pharmaceuticals Jan 2019 - Apr 2020Cambridge, Massachusetts, UsAPI process development and transfer while innovating a scalable synthetic route for a macrocyclic peptide-drug candidate to multi-kilo production for late-phase clinical supply and process validation -
Group Leader And Senior Principal ScientistRa Pharmaceuticals Oct 2013 - Dec 2018Cambridge, Massachusetts, UsCreated modern high-throughput peptide laboratory and research team, implementing state-of-the-art synthetic, automated synthesis and purification, and analytical methods for modified cyclic peptidesPhase I GMP production of peptide drug substance and sterile, injectable drug product with CMO partners, developing specifications for drug substance and drug product as part of regulatory submissions -
Director, Chemical DevelopmentNew England Peptide Sep 2008 - Oct 2013Peptide synthesis, purification, and conjugation method development. Partnering with biotechnology and pharmaceutical companies in developing peptide and protein reagents and lead compounds
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Professor Of ChemistryLouisiana State University Aug 1992 - Sep 2008Baton Rouge, La, UsSynthetic and bioorganic chemistry research directed towards bioactive molecules for application in therapeutic areas such as cancer, Alzheimer's Disease, and infectious disease -
Postodoctoral Research AssociateEth Zurich Sep 1990 - Jun 1992Zürich, ChAdvisor: Albert EschenmoserDesign and synthesis of sugar-modified nucleic acid analogs and their biophysical characterization
Robert Hammer Skills
Robert Hammer Education Details
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University Of Illinois Urbana-Champaign -
University Of MinnesotaOrganic Chemistry -
University Of Illinois Urbana-ChampaignChemistry
Frequently Asked Questions about Robert Hammer
What company does Robert Hammer work for?
Robert Hammer works for Newco
What is Robert Hammer's role at the current company?
Robert Hammer's current role is Discovery Chemistry and Pharmaceutical Development LeadershipMedicinal Chemistry, Drug Discovery, CMC, Peptide and Nucleic Acid Design and Synthesis.
What is Robert Hammer's email address?
Robert Hammer's email address is rh****@****gen.com
What is Robert Hammer's direct phone number?
Robert Hammer's direct phone number is (225) 578*****
What schools did Robert Hammer attend?
Robert Hammer attended University Of Illinois Urbana-Champaign, University Of Minnesota, University Of Illinois Urbana-Champaign.
What skills is Robert Hammer known for?
Robert Hammer has skills like Organic Chemistry, Medicinal Chemistry, Peptides, Chemical Biology, Protein Chemistry, Bioorganic Chemistry, Solid Phase Synthesis, Chromatography, Mass Spectrometry, Molecular Biology, Chemistry, Drug Discovery.
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