Ruani Fernando Email & Phone Number

Ghent, Flemish Region, Belgium

Belgium

R&D project management integrating project, contract and data management with operations support for a dynamic, semi-virtual team. Managing both internal research projects and external collaborations with CRO, biotech and academic partners.:: Design and implementation of an integrated project management and operations platform:: Managing pre-clinical drug development partnerships, from first interactions, negotiating collaborative frameworks through to project completion and deliverables:: Corporate communication and strategy coordination :: Tracking the competitive and partnering landscape

Brussels Area, Belgium

The Brussels Liver Research to Valorisation Alliance (B-Liver) aims to integrate the complementary expertise of VUB’s liver research units to capitalize on common valorisation pathways that transect existing academic liver and safety research lines. B-Liver’s mission is grounded in proven expertise in liver cell biology, pathology and toxicology, which enables the consortium to also extend into higher-risk emerging innovations::: HepaSCREEN :: Builds on a diverse pool of liver based in vitro models, encompassing various cell types, from multiple sources, in different configurations. The common goal between models is to develop better models and tools for toxicity and disease prediction and to develop new therapeutic strategies for liver pathology.:: EvoMED :: Here B-Liver is developing a pipeline of innovative technologies that can fill therapteutic needs in the field of inherited metabolic disorders. :: Public Health and 3R AMs :: The toxicology and 3R aspects of the consortium’s activities also finds impact in a societal context. To this end, the need to ensure safety for both patients and consumers, in addition to regulatory drivers, underlie the public health aspects of B-Liver.

Brussels Area, Belgium

Protection and Exploitation of Research Results: Biomedical Science Masters Program• Exploitation of biomedical research, valorisation of research results at university, introduction to intellectual property rights• Introduction to patents, patent process and patent searching• Introduction to agreements, including confidentiality, material transfer, R&D, options and licensing agreements• Introduction to university start-ups and spin-offs

Brussels Area, Belgium

Retrospective analyses show that safety and efficacy constitute major stumbling blocks during drug development. In particular, drug-induced liver injury (DILI) is the main safety-related reason of post-marketing drug withdrawal and the major cause of acute liver failure in the Western world.The inability of currently available preclinical animal-based safety studies to predict the hepatotoxic potential of new therapeutic agents is one of the underlying causes. Additionally, animal tests are time- and resource-intensive, and remain subject of ethical controversy. The current European regulatory environment also stimulates the shift from in vivo to in vitro testing, in particular because the use of animals for research purposes becomes increasingly prohibited.Consequently, not only the pharmaceutical, but also the chemical and cosmetic industries urgently need in vitro models for toxicological investigations. These should be:(i) human-relevant,(ii) adequately reflect specific tissue function, and,(iii) enable process automation and high-throughput.The In Vitro Toxicology team strives to find an answer to these needs by developing metabolically-competent in vitro liver models based on: - Primary hepatocytes- Stem cells- Connexin-based cellular signalling in liver disease- Identification of genotoxic compounds using a human hepatoma cell-based classifier

Brussels Area, Belgium

Institute Of Neurosciences Of Montpellier

Molecular mechanisms of myelination.

Investigation of cell cycle, proliferation and self-renewal of stem cells in the adult brain

Melbourne, Australia

Investigation of the molecular mechanisms underlying a new class of cognition enhancing drug like peptides: the role of glucose in learning and memory

Genetics Department

Identification of copper dependent phosphorylation sites on MNK, a copper transporter affected in Menke's disease

Phd, Neuroscience

B.Sc. (Hons), Genetics, History And Philosophy Of Science