Ryan Denman Email & Phone Number

Boulder, Colorado, United States

• Works on Procurement assignments with broadly defined objectives
• Contributes to the development of sourcing requirements to support synthetic chemical nucleic acid manufacturing. Researches, evaluates, and supports qualification of products and materials from new and existing.
• Understands and evaluates supplier-s process control strategy used to ensure raw material specifications and quality
• Applies knowledge of organic chemistry to evaluate manufacturing suitability for starting raw materials (such as solvents, reagents, and small molecules), including evaluation of impurity profiles
• Negotiates cost of materials and purchase terms and conditions, as needed
• Supports Agilent-s Supplier Performance Measurement Process and work with suppliers to drive continuous performance improvement

Erie, CO / Eugene, OR

• Pursuing a buy and hold strategy for real estate
• Property manager for 2 units with 5+ years experience
• Built efficient processes to reduce time required to manage 2 rental units to a mere 1 hour average per week

Lafayette, Colorado, United States

• Led process development of 3 oligonucleotide insourcing product lines with broad scope responsibilities to include project planning, project management, process design, process development, raw materials qualification.
• Created a novel cartridge purification process to support 2 product lines, enabling comparable purity to HPLC with a twelvefold increase in throughput
• Led instrument establishment on new HPLC and UHPLC instruments including Agilent 1290 Infinity II Prep, Agilent 1290 Infinity II UHPLC, and PerkinElmer LC300 UHPLC
• Modified stock components of HPLC and UHPLC instrument to suit custom configurations
• Utilized Azure DevOps, Power Automate, Microsoft Lists, and Excel to build productivity tools, automate workflows, and manage project based work
• Site lead for the Kaizen Funnel (a continuous improvement program) which entailed customizing Azure DevOps tools, interacting with idea submitters to develop ideas and create plans of implementation

Lafayette, Colorado, United States

Lafayette, Colorado, United States

Lafayette, Colorado, United States

• Developed new HPLC/UHPLC methods for analysis and purification of oligonucleotides 15 to 128 bases long
• Characterized oligonucleotides using HPLC, UHPLC, mass spectrometry, and UV/Vis instruments
• Expanded capability of Akta oligo synthesizer by creating a custom instrument configuration
• Performed a feasibility study for designing and building a novel oligonucleotide synthesizer instrument
• Collaborated with a team to establish new tenant of Signals electronic lab notebook (ELN) with 97 users
• Performed admin duties to manage new and existing users of Signals ELN

Boulder, Colorado

• Performed process development (synthesis, deprotection, purification, TFF) on active pharmaceutical ingredient (API) oligonucleotides
• Assisted in a platform validation project of 2 related oligonucleotides, including execution of design of experiments (DoE) studies and data integrity of reports, notebook pages, and related documents
• Proficient with equipment including HPLC, Akta Oligo Pilot, Akta Explorer, Akta Pure, UV/Vis, Scilog UF
• Recorded experimental data in an electronic laboratory notebook
• Served as lead for group safety and NCO (neat, clean, and orderly) implementation for FDA PAI inspection
• Advanced proficiency in Microsoft Office products, moderate proficiency in Agilent software programs (ChemStation, ELN, UV/vis), and basic proficiency in statistics, R and Python programming languages

Eugene, Oregon

• Performed synthetic organic chemistry and purification on milligram to hundred-gram scale of fluorescent dyes
• Synthesized fluorescent dyes: BODIPY, Alexa Fluor, Cy Dyes, coumarins, SYBR, rhodamine, DAPI, and others
• Developed more robust chemistry methods and assisted in R&D tech transfer to manufacturing
• Independently planned and executed manufacturing work orders to adhere to goals and deadlines
• Drove improvement and reproducibility of processes through revision of batch records and SOPs
• Proficient with manufacturing methodologies such as 5S and Practical Process Improvement (PPI)

Boulder, Colorado, United States

• Extracted cannabis essential oils from plant matter using a closed-loop butane extractor
• Developed concepts for advanced extractors to increase efficiency and capacity
• Ensured regulatory compliance through working methods and inventory tracking
• Supervised training of new employees
• Designed, built, and troubleshot apparatuses to improve efficiency of extractions and product creation

Boulder, Colorado, United States

• Tutored 51 students one-on-one, for a total of 327 hours in General and Organic Chemistry

Boulder, Colorado

• 3+ years organic chemistry laboratory experience with increasing levels of responsibility
• Synthesized new organic compounds using wet chemistry and air free synthesis methods
• Operated specialized equipment for characterization including NMR, IR, GPC, GC/MS, and MALDI
• Presented work completed through monthly reports and group presentations
• Documented detailed experimental procedures and results clearly in a laboratory notebook
• Managed lab equipment maintenance: rotovap, dry solvent system, gas cylinders, and vacuum pumps

• Led an eight-person team tasked with data analysis on TS/SCI classified projects
• Graduated Airman Leadership School
• Senior Airman Below the Zone (Early promotion for outstanding performance)
• AFSC / RI = 9S100

Master Of Science (M.S.), Chemistry

Bachelor Of Science (Bs), Chemistry

Associate Of Arts (A.A.), General Studies