Ryan Denman Email and Phone Number
Experienced process developer with a demonstrated history of working in the biotechnology industry. Skilled in Organic Chemistry, Spectroscopy, Deductive Reasoning, Science, Leadership, and Statistics. Strong research professional with a Master of Science (M.S.) focused in Organic Materials Chemistry from University of Colorado Boulder.
Agilent Technologies
View- Website:
- agilent.com
- Employees:
- 56379
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Oligonucleotide Materials ExpertAgilent Technologies Mar 2024 - PresentBoulder, Colorado, United States• Works on Procurement assignments with broadly defined objectives• Contributes to the development of sourcing requirements to support synthetic chemical nucleic acid manufacturing. Researches, evaluates, and supports qualification of products and materials from new and existing suppliers• Understands and evaluates supplier-s process control strategy used to ensure raw material specifications and quality• Applies knowledge of organic chemistry to evaluate manufacturing suitability for starting raw materials (such as solvents, reagents, and small molecules), including evaluation of impurity profiles• Negotiates cost of materials and purchase terms and conditions, as needed• Supports Agilent-s Supplier Performance Measurement Process and work with suppliers to drive continuous performance improvement• Monitors supplier performance and takes appropriate action with suppliers, including issuing of SCARs, to resolve issues in timely manner• Collaborates cross-functionally within Agilent NASD and partners with suppliers to ensure they can support Agilent NASD-s continuing, rapid business growth• Contributes to cost reduction efforts to reduce supply chain cost/cost of goods (COGS), while maintaining a continuing reliable source of supply• Develops, communicates, and implements rolling-forecast requirements with critical suppliers -
Real Estate InvestorSelf-Employed Oct 2017 - PresentErie, Co / Eugene, Or• Pursuing a buy and hold strategy for real estate• Property manager for 2 units with 5+ years experience• Built efficient processes to reduce time required to manage 2 rental units to a mere 1 hour average per week
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Senior Process Development ChemistRevvity May 2023 - Mar 2024Lafayette, Colorado, United States• Led process development of 3 oligonucleotide insourcing product lines with broad scope responsibilities to include project planning, project management, process design, process development, raw materials qualification and supply chain management. Efforts of insourcing team have realized greater than $1M yearly savings• Created a novel cartridge purification process to support 2 product lines, enabling comparable purity to HPLC with a twelvefold increase in throughput• Led instrument establishment on new HPLC and UHPLC instruments including Agilent 1290 Infinity II Prep, Agilent 1290 Infinity II UHPLC, and PerkinElmer LC300 UHPLC• Modified stock components of HPLC and UHPLC instrument to suit custom configurations• Utilized Azure DevOps, Power Automate, Microsoft Lists, and Excel to build productivity tools, automate workflows, and manage project based work• Site lead for the Kaizen Funnel (a continuous improvement program) which entailed customizing Azure DevOps tools, interacting with idea submitters to develop ideas and create plans of implementation -
Senior Process Development ChemistPerkinelmer, Inc. Oct 2022 - May 2023Lafayette, Colorado, United States -
Process Development ChemistPerkinelmer, Inc. Jan 2022 - Sep 2022Lafayette, Colorado, United States -
Process Development ChemistHorizon Discovery Jan 2021 - Dec 2021Lafayette, Colorado, United States• Developed new HPLC/UHPLC methods for analysis and purification of oligonucleotides 15 to 128 bases long• Characterized oligonucleotides using HPLC, UHPLC, mass spectrometry, and UV/Vis instruments• Expanded capability of Akta oligo synthesizer by creating a custom instrument configuration• Performed a feasibility study for designing and building a novel oligonucleotide synthesizer instrument• Collaborated with a team to establish new tenant of Signals electronic lab notebook (ELN) with 97 users• Performed admin duties to manage new and existing users of Signals ELN -
Research AssociateAgilent Technologies Oct 2017 - Dec 2020Boulder, Colorado• Performed process development (synthesis, deprotection, purification, TFF) on active pharmaceutical ingredient (API) oligonucleotides• Assisted in a platform validation project of 2 related oligonucleotides, including execution of design of experiments (DoE) studies and data integrity of reports, notebook pages, and related documents• Proficient with equipment including HPLC, Akta Oligo Pilot, Akta Explorer, Akta Pure, UV/Vis, Scilog UF• Recorded experimental data in an electronic laboratory notebook• Served as lead for group safety and NCO (neat, clean, and orderly) implementation for FDA PAI inspection• Advanced proficiency in Microsoft Office products, moderate proficiency in Agilent software programs (ChemStation, ELN, UV/vis), and basic proficiency in statistics, R and Python programming languages -
Scientist IiThermo Fisher Scientific Jan 2015 - Sep 2017Eugene, Oregon• Performed synthetic organic chemistry and purification on milligram to hundred-gram scale of fluorescent dyes• Synthesized fluorescent dyes: BODIPY, Alexa Fluor, Cy Dyes, coumarins, SYBR, rhodamine, DAPI, and others• Developed more robust chemistry methods and assisted in R&D tech transfer to manufacturing• Independently planned and executed manufacturing work orders to adhere to goals and deadlines• Drove improvement and reproducibility of processes through revision of batch records and SOPs• Proficient with manufacturing methodologies such as 5S and Practical Process Improvement (PPI) -
Chemical EngineerHis Way Herbs Llc. Feb 2014 - Dec 2014Boulder, Colorado, United States• Extracted cannabis essential oils from plant matter using a closed-loop butane extractor• Developed concepts for advanced extractors to increase efficiency and capacity• Ensured regulatory compliance through working methods and inventory tracking• Supervised training of new employees• Designed, built, and troubleshot apparatuses to improve efficiency of extractions and product creation
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Freelance Chemistry TutorSelf-Employed Aug 2013 - Aug 2014Boulder, Colorado, United States• Tutored 51 students one-on-one, for a total of 327 hours in General and Organic Chemistry
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Research Assistant / Teaching AssistantUniversity Of Colorado Aug 2009 - Aug 2013Boulder, Colorado• 3+ years organic chemistry laboratory experience with increasing levels of responsibility• Synthesized new organic compounds using wet chemistry and air free synthesis methods• Operated specialized equipment for characterization including NMR, IR, GPC, GC/MS, and MALDI• Presented work completed through monthly reports and group presentations• Documented detailed experimental procedures and results clearly in a laboratory notebook• Managed lab equipment maintenance: rotovap, dry solvent system, gas cylinders, and vacuum pumps• Proficient with a variety of software including MS Office, ChemDraw, and Mestranova• Led weekly recitations of 20 students; lectured, answered questions, and guided discussion of the material• Taught lecture of 120 students for the professor when absent• Led weekly laboratory sections of 20 students, teaching proper experimental techniques and lab safety -
Satellite Operations Data AnalystUnited States Air Force Jun 2003 - Jun 2007• Led an eight-person team tasked with data analysis on TS/SCI classified projects• Graduated Airman Leadership School• Senior Airman Below the Zone (Early promotion for outstanding performance)• AFSC / RI = 9S100
Ryan Denman Education Details
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Chemistry -
Chemistry -
General Studies
Frequently Asked Questions about Ryan Denman
What company does Ryan Denman work for?
Ryan Denman works for Agilent Technologies
What is Ryan Denman's role at the current company?
Ryan Denman's current role is Strategic Sourcing Professional.
What schools did Ryan Denman attend?
Ryan Denman attended University Of Colorado Boulder, University Of Central Florida, Brevard Community College.
Who are Ryan Denman's colleagues?
Ryan Denman's colleagues are Ok Ok, Ding Nguyen, Andew Williams, Lee Carol, Vikas Tyagi, Lisa Ziemer, Jay Tee.
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