Ryan Longchamps
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Ryan Longchamps Email & Phone Number

Associate Director, Statistical Genetics at Ionis Pharmaceuticals, Inc.
Location: Washington DC-Baltimore Area, United States, United States 8 work roles 2 schools
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Current company
Role
Associate Director, Statistical Genetics
Location
Washington DC-Baltimore Area, United States, United States
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Who is Ryan Longchamps? Overview

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Ryan Longchamps is listed as Associate Director, Statistical Genetics at Ionis Pharmaceuticals, Inc., a company with 1267 employees, based in Washington DC-Baltimore Area, United States, United States. AeroLeads shows a matched LinkedIn profile for Ryan Longchamps.

Ryan Longchamps previously worked as Assistant Director, Statistical Genetics at Ionis Pharmaceuticals, Inc. and Senior Research Scientist at Deep Genomics. Ryan Longchamps holds Doctor Of Philosophy (Phd), Human Genetics from The Johns Hopkins University School Of Medicine.

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Ionis Pharmaceuticals, Inc.

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About Ryan Longchamps

Computational/Statistical Geneticist with a PhD in Human Genetics and 8+ years expertise in genomic data analysis from large prospective public health cohorts with a strong background in statistical analysis, target identification, cardiovascular disease, mitochondrial genetics, and biology. Currently an Assistant Director of Statistical Genetics at Ionis Pharmaceuticals as a member of the Human Genetics team. Fluent in R, familiar with Python, skilled in GWAS, polygenic risk scores, Mendelian randomization, LD score regression, imputation, fine-mapping, as well as extensive experience analyzing summary statistics, array, NGS, gene- and variant-level data.

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Ionis Pharmaceuticals, Inc.
Ionis Pharmaceuticals, Inc.
Associate Director, Statistical Genetics
Washington, DC, US
Website
Employees
1267
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8 roles

Ryan Longchamps work experience

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Postdoctoral Research Fellow

  • Generated simulation data and evaluated the efficiency of a novel summary statistics-based cross-ancestry fine-mapping method compared to pre-existing methods.
  • Performed cross-ancestry fine-mapping and functional annotation in 100,000 individuals across 30 phenotypes from the UK Biobank, BioBank Japan and Taiwan Biobank.
  • Collaboratively contributed R and Python code for the development of a GWAS summary statistics QC pipeline.
Sep 2019 - May 2021

Graduate Student In Human Genetics

Baltimore, MD

  • Performed genome wide association study (GWAS) in 470,000 individuals for mitochondrial DNA copy number as lead analyst for the CHARGE consortium in collaboration with 15 cohorts across the US and Europe.
  • Employed Mendelian Randomization and Polygenic Risk Scores to elucidate the relationship between mitochondrial DNA copy number and Cardiovascular Disease.
  • Developed algorithms to calculate mitochondrial DNA copy number from genotyping arrays, whole genome and whole exome sequencing data that contributed to 9 published manuscripts and 2 publications in preparation.
  • Demonstrated an association of mitochondrial heteroplasmy with overall mortality and Cardiovascular disease in 20,000 individuals from the CHARGE consortium.
  • Optimized high throughput mitochondrial DNA sequencing enabling 384x multiplexing within a single flow-cell.
  • Directed development of allele-specific CRISPR-Cas9 cell lines targeting genes affecting mitochondrial DNA replication efficiency and fidelity.
Aug 2013 - Sep 2019

Post-Bac Irta

Bethesda, MD

  • Investigated the use of microRNAs measured from whole blood as minimally invasive biomarkers for non-alcoholic fatty liver disease progression.
  • Optimized labrotory Ion Torrent Personal Genome Machine sequencing protocol for gut microbiome samples.
Feb 2012 - May 2013
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Colleagues at Ionis Pharmaceuticals, Inc.

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2 education records

Ryan Longchamps education

FAQ

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What company does Ryan Longchamps work for?

Ryan Longchamps works for Ionis Pharmaceuticals, Inc..

What is Ryan Longchamps's role at Ionis Pharmaceuticals, Inc.?

Ryan Longchamps is listed as Associate Director, Statistical Genetics at Ionis Pharmaceuticals, Inc..

Where is Ryan Longchamps based?

Ryan Longchamps is based in Washington DC-Baltimore Area, United States, United States while working with Ionis Pharmaceuticals, Inc..

What companies has Ryan Longchamps worked for?

Ryan Longchamps has worked for Ionis Pharmaceuticals, Inc., Deep Genomics, Massachusetts General Hospital, Broad Institute Of Mit And Harvard, and The Johns Hopkins University School Of Medicine.

Who are Ryan Longchamps's colleagues at Ionis Pharmaceuticals, Inc.?

Ryan Longchamps's colleagues at Ionis Pharmaceuticals, Inc. include Kym Bradley, Sinéad Williams, Zheng Li, Johanna Golias, Pharm.D., and Stephanie Mongelluzzo.

How can I contact Ryan Longchamps?

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What schools did Ryan Longchamps attend?

Ryan Longchamps holds Doctor Of Philosophy (Phd), Human Genetics from The Johns Hopkins University School Of Medicine.

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